Medicinal Herbals with Antiplatelet Properties Benefit in Coronary Atherothrombotic Diseases

Thrombosis Pub Date : 2016-03-14 DOI:10.1155/2016/5952910
N. H. Mohd Nor, F. Othman, Eusni Rahayu Mohd Tohit, S. Md Noor
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引用次数: 20

Abstract

Coronary atherothrombotic diseases such as coronary artery disease, peripheral vascular disease, cerebrovascular disease, and heart failure are the serious concerns of the thrombus formed in blood vessels. Anticoagulant and antiplatelet drugs are the cornerstones of the management of these diseases. To prevent the recurrence of these diseases, double antiplatelet drugs such as aspirin and clopidogrel has been the standard management in most hospitals. However, aspirin resistance and clopidogrel inefficient effects due to noncompliance with double drugs regimen can cause a sinister effect on patients. Medicinal plants serve as a greater resource for new medication and their potential currently became a topic of interest to the researchers all over the world. Traditionally, certain herbs have been used as a treatment for heart diseases but have been investigated for their antiplatelet properties. This current review explained few traditional antithrombotic herbals and their antiplatelet properties in vitro and in vivo and this is to be deeply discussed in further research.
具有抗血小板特性的草药对冠状动脉粥样硬化性疾病有益
冠状动脉粥样硬化性疾病,如冠状动脉疾病、外周血管疾病、脑血管疾病和心力衰竭,是血管内形成血栓的严重问题。抗凝血和抗血小板药物是治疗这些疾病的基石。为了防止这些疾病的复发,阿司匹林和氯吡格雷等双重抗血小板药物已成为大多数医院的标准管理。然而,由于不遵守双药方案,阿司匹林耐药性和氯吡格雷无效效应会对患者造成不良影响。药用植物是开发新药的重要资源,其潜力已成为世界各国研究人员关注的热点。传统上,某些草药已被用作治疗心脏病,但已调查其抗血小板特性。本文综述了几种传统抗血栓药物及其体内体外抗血小板性能,有待进一步深入研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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