Pre pregnant weight a risk factor for Gestational Diabetes Mellitus

B. P, John B Dominic, Juby Ann
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Abstract

Introduction: Gestational Diabetes Mellitus is defined as glucose intolerance that is first recognized during pregnancy. This is associated with increased risk for adverse perinatal outcomes as well as long term complications of obesity and type 2 diabetes mellitus in mother and their children. The aim of this study was to identify the risk factors for Gestational diabetes mellitus. Methodology: Study design: Prospective nested case control study Sample size:With an estimated Odds ratio of 2 for risk factors, we need 100 GDM and 200 controls and with an estimate of 10% as GDM, we recruited a sample of 1000 Primigravidae patients attending the Out Patient Clinic at SAT Hospital, in the first trimester followed up and grouped into cases and controls depending on the GTT results. Results: One thousand Primigravids were recruited and followed up. 960 patients were followed up till delivery and data collected; 240 developed gestational diabetes mellitus (cases ) and the remaining 720 were taken as controls. The mean age of the study population 23.39yrs and that of the cases were 24.68yrs and that of the controls were 22.96yrs with significant difference. The place of residence urban or rural, the educational status or the socioeconomic status did not
孕前体重是妊娠期糖尿病的危险因素
妊娠期糖尿病被定义为在妊娠期间首次发现的葡萄糖耐受不良。这与不良围产期结局以及母亲及其子女肥胖和2型糖尿病的长期并发症的风险增加有关。本研究的目的是确定妊娠期糖尿病的危险因素。研究方法:研究设计:前瞻性巢式病例对照研究样本量:风险因素的比值比估计为2,我们需要100例GDM和200例对照,估计10%为GDM,我们招募了1000例在SAT医院门诊就诊的初孕患者,在妊娠早期随访,并根据GTT结果分为病例和对照组。结果:共招募了1000例原鸟,并进行了随访。960例患者随访至分娩并收集数据;240例发生妊娠期糖尿病(例),其余720例作为对照组。研究人群平均年龄23.39岁,病例平均年龄24.68岁,对照组平均年龄22.96岁,差异有统计学意义。居住地是城市还是农村,教育程度还是社会经济地位都没有差别
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