Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant

Abstract

DOI : 10.26650/IstanbulJPharm.2019.18001 The aim of this study is to evaluate the antimicrobial, antioxidant, and antigenotoxic activity of extracts obtained from Diplotaenia cachrydifolia Boiss, which is traditionally used for food and medical treatment by the local people of Hakkâri Province (Turkey). As a result of this study, the extracts of D. cachrydifolia exhibited a broad antimicrobial spectrum and high antimicrobial activity. It was also observed that the extracts had a high antioxidant activity. The DPPH IC50 values of the extracts were 2.5234 µg/mL, 6.0075 µg/mL, and 29.1974 µg/mL for ethanol, acetone, and hexane, respectively. The highest phenol content was found to be 55.36±0.035 μg/mL for ethanol. Furthermore, the ethanol extract was found to have a protective effect against mitomycin C-induced genotoxicity. D. cachrydifolia has a high biological activity; therefore, it is anticipated that future pharmacological studies will shed more light on this plant.  Cite this article as : Ugras S, Ulger S, Goc Rasgele P (2019). Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant. Istanbul J Pharm 49 (2): 45-52.