Fersis-Phage against Purulent-Inflammatory (Staphylococcal, Streptococcal) Pathologies

T. Gabisonia, I. Giorgadze, N. Topuria, L. Chanishvili, M. Nadiradze, N. Chakhunashvili, T. Katamadze, M. Loladze, N. Tamarashvili, M. AlibegaSvili, Kal, T. arishvili, T. Eliava
{"title":"Fersis-Phage against Purulent-Inflammatory (Staphylococcal, Streptococcal) Pathologies","authors":"T. Gabisonia, I. Giorgadze, N. Topuria, L. Chanishvili, M. Nadiradze, N. Chakhunashvili, T. Katamadze, M. Loladze, N. Tamarashvili, M. AlibegaSvili, Kal, T. arishvili, T. Eliava","doi":"10.36648/1989-8436.10.1.89","DOIUrl":null,"url":null,"abstract":"The problem of prevention and treatment of infectious diseases in infectious and non-infectious clinics is one of the priorities in practical public health. The application of phage preparations, as antimicrobial medioprophylactic remedies against staphylo- and streptococcal infections seems to be an alternative to antibiotics and sulfonamide preparations. Pronounced tendency of circulating pathogenic bacterial strains towards reducing sensitivity to antibiotics, also caused by irrational use of the latter, further confirmed our decision to create a new phage preparation. Based on the conducted studies the new variant of Fersis, an active, multivalent phage preparation, consisting phages against staphylococci (S. aureus, S. epidermidis) and streptococci (S. pyogenes, S. viridians, S. sanguis, S. salivarius, S. agalacticae) causing oral cavity infectious diseases, has been prepared.","PeriodicalId":8142,"journal":{"name":"Archives of Clinical Microbiology","volume":"41 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Clinical Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36648/1989-8436.10.1.89","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2

Abstract

The problem of prevention and treatment of infectious diseases in infectious and non-infectious clinics is one of the priorities in practical public health. The application of phage preparations, as antimicrobial medioprophylactic remedies against staphylo- and streptococcal infections seems to be an alternative to antibiotics and sulfonamide preparations. Pronounced tendency of circulating pathogenic bacterial strains towards reducing sensitivity to antibiotics, also caused by irrational use of the latter, further confirmed our decision to create a new phage preparation. Based on the conducted studies the new variant of Fersis, an active, multivalent phage preparation, consisting phages against staphylococci (S. aureus, S. epidermidis) and streptococci (S. pyogenes, S. viridians, S. sanguis, S. salivarius, S. agalacticae) causing oral cavity infectious diseases, has been prepared.
噬菌体抗脓性炎症(葡萄球菌,链球菌)病理
在传染病和非传染病诊所预防和治疗传染病的问题是实际公共卫生的优先事项之一。噬菌体制剂的应用,作为抗葡萄球菌和链球菌感染的抗微生物中预防性补救措施,似乎是抗生素和磺胺制剂的替代品。流行致病菌菌株对抗生素敏感性降低的明显趋势,也是由抗生素的不合理使用引起的,进一步证实了我们创造一种新的噬菌体制剂的决定。在已有研究的基础上,制备了Fersis的新变种,这是一种活性的多价噬菌体制剂,由抗引起口腔传染病的葡萄球菌(金黄色葡萄球菌、表皮葡萄球菌)和链球菌(化脓性葡萄球菌、葡萄球菌、血源性葡萄球菌、唾液链球菌、无乳链球菌)的噬菌体组成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信