Inhalation Exposure to PCB from Contaminated Indoor Air—How Much Is Absorbed into the Blood?

Pollutants Pub Date : 2021-09-01 DOI:10.3390/pollutants1030015

M. Kraft, K. Rauchfuss, H. Fromme, L. Grün, S. Sievering, B. Köllner, Y. Chovolou

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引用次数: 6

Abstract

Polychlorinated biphenyls (PCBs) were used in many construction products until their banning in the 1970s and 1980s. Nonetheless, exposure to PCBs from contaminated indoor air is still an important public health issue. The aim of our study was to estimate the contribution of PCB congeners in indoor air to the levels of PCBs in human blood. We analyzed all 209 PCB congeners in the blood of 35 individuals exposed to PCBs from contaminated indoor air. For each individual, we measured the six marker indicators PCB28, PCB52, PCB101, PCB138, PCB153 and PCB180 in indoor air at the workplace. Statistically significant correlations between PCB-contaminated indoor air and the existence of the sum of mono-, di-, tri-, tetra- and pentachlorinated biphenyls (∑PCB1–127) in the blood of the exposed individuals were found. We quantified the proportions of PCBs that are absorbed into the blood via inhalation of contaminated indoor air. Inhalation of PCBs from contaminated indoor air, especially in children, adolescents and younger adults, may lead to PCB blood burdens that are higher than general PCB background levels or in approximately the same range.

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从被污染的室内空气中吸入多氯联苯——有多少被血液吸收?

多氯联苯(PCBs)在许多建筑产品中使用，直到20世纪70年代和80年代才被禁止。尽管如此，从受污染的室内空气中接触多氯联苯仍然是一个重要的公共卫生问题。我们研究的目的是估计室内空气中多氯联苯同系物对人体血液中多氯联苯水平的贡献。我们分析了35名暴露于受污染室内空气中多氯联苯的个体血液中的所有209种多氯联苯同系物。对于每个人，我们测量了工作场所室内空气中PCB28、PCB52、PCB101、PCB138、PCB153和PCB180六种标记指标。多氯联苯污染室内空气与暴露人群血液中一、二、三、四、五氯联苯总量(∑PCB1-127)存在显著相关性。我们量化了通过吸入被污染的室内空气而被血液吸收的多氯联苯的比例。从受污染的室内空气中吸入多氯联苯，特别是儿童、青少年和年轻人，可能导致多氯联苯血液负荷高于一般多氯联苯背景水平或大致相同的范围。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pollutants

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