A Systematic Review and Meta-Analysis of the Proportion and Antimicrobial Susceptibility Pattern of Escherichia coli O157:H7 from Different Human Foods in Ethiopia

Archives of Clinical Microbiology Pub Date : 2020-01-01 DOI:10.36648/1989-8436.11.3.114

Tigist Engda, A. Atnafu, M. Alemayehu

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Abstract

Background: Escherichia coli O157: H7 is shiga toxinproducing Escherichia coli which is recognized as an important cause of diarrhea, hemorrhagic colitis and hemolytic-uremic syndrome worldwide. The aim of this systematic review and meta-analysis is to assess the burden of Escherichia coli O157:H7 and its antibiotic resistance pattern in different foods in Ethiopia. Methods: The literature search was conducted to identify all published articles reporting the proportion and antimicrobial susceptibility pattern of shiga toxin producing Escherichia coli O157:H7 in foods. From all screened articles, 21 studies were eligible for i¬A‚Ânal systematic review and meta-analysis. Statistical analysis was done by using STATA14 software. Results: The pooled proportion of Escherichia coli O157:H7 is 0.05 (95% CI, 0.04 to 0.07%). Moreover, Shiga toxin-producing Escherichia coli strains were found to be highly resistant to Chloramphenicol, Tetracycline, Erythromycin and Streptomycin, with a pooled resistance ratio of 79.72, 63.44, 52.65, and 50.77%, respectively. On the other hand, comparably low levels of resistance ratio were noted to Nitrofurantoin 7.54% and Norfloxacin 9.72%. Conclusion: The overall burden of Escherichia coli O157:H7 is low. However, it indicates the probability of food contamination by Escherichia coli O157:H7. And, E. coli O157:H7 showed resistance to Chloramphenicol, Tetracycline, Erythromycin and Streptomycin.

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埃塞俄比亚不同人类食物中O157:H7大肠杆菌比例及药敏模式的系统回顾和meta分析

背景:大肠杆菌O157: H7是产志贺毒素的大肠杆菌，在世界范围内被认为是腹泻、出血性结肠炎和溶血性尿毒症综合征的重要病因。本系统综述和荟萃分析的目的是评估埃塞俄比亚不同食物中大肠杆菌O157:H7的负担及其抗生素耐药性模式。方法:采用文献检索法，对所有报道食品中产志贺毒素大肠杆菌O157:H7的比例及药敏规律的文献进行检索。从所有筛选的文章中，有21项研究符合i - A， Â的系统评价和荟萃分析。采用STATA14软件进行统计分析。结果:大肠杆菌O157:H7的合并比例为0.05 (95% CI为0.04 ~ 0.07%)。产志贺毒素大肠埃希菌对氯霉素、四环素、红霉素和链霉素均有高度耐药，总耐药率分别为79.72、63.44、52.65和50.77%。呋喃妥因耐药率为7.54%，诺氟沙星耐药率为9.72%。结论:大肠杆菌O157:H7总体负荷较低。然而，它表明食品被大肠杆菌O157:H7污染的可能性。大肠杆菌O157:H7对氯霉素、四环素、红霉素和链霉素耐药。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Archives of Clinical Microbiology

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