Simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer nano drugs complexes

A. Heidari, R. Gobato
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引用次数: 11

Abstract

In the current work, simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer Nano drugs complexes are studied. A technique that helps to achieve representative biopsies and that would enable accurate and early in vivo diagnosis is needed. This tool should detect lesions in pre–malignant/early stages and assess large tissue areas in real–time to decrease sampling errors. Several techniques have been tested for biopsy guidance, such as optical coherence tomography (OCT), white light reflectance (WLR), simultaneous detection of intra– and inter–molecular paramagnetic relaxation enhancements in DNA/RNA of gum cancer cells–anti–cancer Nano drugs complexes.
牙龈癌细胞-抗癌纳米药物复合物DNA/RNA分子内和分子间顺磁弛豫增强的同时检测
本研究旨在同时检测牙龈癌细胞-抗癌纳米药物复合物中DNA/RNA的分子内和分子间顺磁弛豫增强。需要一种有助于实现有代表性的活组织检查并能够进行准确和早期体内诊断的技术。该工具应在恶性前/早期阶段检测病变,并实时评估大组织区域,以减少采样误差。已经测试了几种用于活检指导的技术,例如光学相干断层扫描(OCT),白光反射(WLR),同时检测牙龈癌细胞DNA/RNA的分子内和分子间顺磁弛豫增强-抗癌纳米药物复合物。
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