Hormone Therapy as A New Hope for Achondroplasia Patients

B. Supartono, Ayola Dewi Utami, Abyanka Rayhan Fuadi, Bintang Bayu Aryandi
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引用次数: 1

Abstract

Achondroplasia is a disorder of child bone growth due to gene mutation of growth factor receptor. Short stature is a major problem. Efforts to increase height are still a challenge. The method performed so far is the lengthening of the limbs with various complications and risks of re-surgery. A promising new alternative without surgery is the administration of growth hormone therapy. This review aims to find out the safety and effectiveness of hormone therapy. The review method used is a narrative review. The review results showed that growth hormone therapy is safe and effective. The review concludes that growth hormone therapy has been proven to be safe and effective in increasing the height of achondroplasia patients.
激素治疗是软骨发育不全患者的新希望
软骨发育不全是由于生长因子受体基因突变引起的儿童骨骼生长障碍。身材矮小是个大问题。努力增加身高仍然是一个挑战。目前采用的方法是延长肢体,有各种并发症和再次手术的风险。一种不需要手术的有希望的新选择是使用生长激素疗法。本综述旨在了解激素治疗的安全性和有效性。使用的复习方法是叙述性复习。综述结果表明,生长激素治疗是安全有效的。本综述认为,生长激素治疗已被证明对软骨发育不全患者的增高是安全有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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