“Nanotracker” for superior early disease diagnosis

Abstract

Pu and coworkers developed a disease biomarker-activatable polyfluorophore nanosensor that comprises protease-reactive peptide brushes, self-immolative linkers, and renal clearance/tumor-targeting moiety-conjugated fluorophore units, for noninvasive near-infrared fluorescence imaging and urinalysis, enabling superior early disease diagnosis.