Assessment of prognostic markers of alopecia areata in pediatric patients

Jhini Nayak, K. Bhatia, C. Namdeo
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Abstract

Alopecia areata (AA) is associated with impairment of psychological health being more pronounced in pediatric population. Hence, it becomes imperative to study the AA in pediatric population so that early diagnosis and adequate treatment can be initiated at early stage to prevent further morbidity associated with the condition. This observational study was conducted in the department of dermatology venereology and leprosy, SAIMS and PG institute, Indore, India after obtaining approval from the IEC. The study included 14 children with AA who visited the hospital over the period of 1 year. Results showed that Mean age of the patients was 8.8±3.423 years with M:F ratio of 3:4. AA subtotalis was found to be most frequent (57.1%). The mean duration of alopecia was reported to be 9.3±7.965 months. The most common finding was the presence of a single patch (35.7%) and 50% of subjects have had a single episode of the disease. 64.3% of children had involvement of multiple sites with scalp being the most common (85.7%). There is high prevalence of markers of disease severity and activity amongst pediatric patients with AA. High prevalence of nail changes, mark hair (64.3%), coudability hair (50.0%), yellow dots (42.8.0%), black dots (78.6%), S. vellus hair (28.6%) shows that children have high chance of AA progressing to severe forms. There is high prevalence of markers of disease severity and activity amongst pediatric patients with AA with AA subtotalis more common among children as compared to the patchy type.
儿科斑秃患者预后指标的评估
斑秃(AA)与心理健康损害的关系在儿科人群中更为明显。因此,有必要研究儿童群体的AA,以便早期诊断和适当的治疗,以防止进一步的发病。这项观察性研究是在获得IEC批准后,在印度印多尔的皮肤病性病和麻风病、SAIMS和PG研究所进行的。这项研究包括了14名在一年的时间里到医院就诊的嗜酒成瘾儿童。结果患者平均年龄为8.8±3.423岁,M:F比为3:4。其中以AA型亚全最常见(57.1%)。平均脱发持续时间为9.3±7.965个月。最常见的发现是单一斑块的存在(35.7%),50%的受试者有一次疾病发作。64.3%的儿童有多部位受累,以头皮最常见(85.7%)。在儿童AA患者中,疾病严重程度和活动标志物的流行率很高。甲变、斑纹毛(64.3%)、可染毛(50.0%)、黄点(42.8.0%)、黑点(78.6%)、牛皮样毛(28.6%)的高发率表明儿童AA发展为重度的几率较高。在儿童AA患者中,疾病严重程度和活动标志物的患病率很高,与斑状型相比,AA亚全型在儿童中更为常见。
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