MODELING REACTION MECHANISM OF GLUTAMATE CARBOXYPEPTIDASE – A MEMBER OF THE POLYENZYME CHAIN OF N-ACETYLASPARTATE

Abstract

Computational methods of molecular modeling are used to simulate the reaction mechanism of hydrolysis of N-acetyl-L-aspartyl-L-glutamate catalyzed by glutamate carboxypeptidase II to N-acetylaspartate and glutamate.