Investigation of the potential probiotic effects of lactic acid bacteria and cell-free supernatants against important pathogens leading to wound infections

IF 0.7 4区生物学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Minerva Biotechnology and Biomolecular Research Pub Date : 2023-03-01 DOI:10.23736/s2724-542x.22.02935-2

Ozgenur Yilmaz, S. Turkyilmaz

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引用次数: 1

Abstract

In recent years, several in vitro studies have revealed that some of the LAB strains and their Cell-free supernatants (CFSs) have shown antibacterial activities and promising tools to prevent or disperse the bio�lm formation of dermatological pathogens. In this study, it was aimed to investigate the antibacterial effects of LAB active cultures and CFSs against P. aeruginosa and S. aureus which were related to wound infections, as well as the inhibitory effects of CFSs on the bio�lm formation of pathogens and destroying bio�lms. The current results indicated that some of the LAB active cultures and CFSs have shown antibacterial properties against pathogens; furthermore, it was determined that some of the CFSs have shown powerful inhibitory effects on bio�lm formation and destroying bio�lms. All data together signify a great ability of the applications of CFSs as antibacterial and bio�lm removal compounds that could be very suitable to control wound infections caused by these pathogens

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乳酸菌和无细胞上清液对导致伤口感染的重要病原体潜在益生菌作用的研究

近年来，一些体外研究表明，一些LAB菌株及其无细胞上清(CFSs)具有抗菌活性，是防止或分散皮肤病病原体生物膜形成的有前途的工具。本研究旨在探讨乳酸菌活性培养物和CFSs对与伤口感染相关的铜绿假单胞菌和金黄色葡萄球菌的抑菌作用，以及CFSs对病原菌生物膜形成和破坏生物膜的抑制作用。目前的研究结果表明，部分乳酸菌活性培养物和CFSs具有抗菌作用;此外，我们还确定了一些CFSs对生物膜的形成和破坏具有较强的抑制作用。所有这些数据表明，CFSs作为抗菌和生物膜去除化合物的应用能力很强，非常适合控制这些病原体引起的伤口感染

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来源期刊

Minerva Biotechnology and Biomolecular Research BIOTECHNOLOGY & APPLIED MICROBIOLOGY-

CiteScore

1.50

自引率

30.00%

发文量