Hong Xue, Weidong Li, Cheng-kang Xu, Yiran Liu, Xufang Wang
{"title":"Effects of high + Gz exposure on saliva α-amylase of fighter pilots","authors":"Hong Xue, Weidong Li, Cheng-kang Xu, Yiran Liu, Xufang Wang","doi":"10.3760/CMA.J.ISSN.1007-6239.2014.02.002","DOIUrl":null,"url":null,"abstract":"Objective To investigate the influence of +Gz acceleration on saliva a-amylase (SAA) of pilots,so as to assess the feasibility of taking SAA as an indicator of +Gz stress on pilots.Methods Saliva was collected from 47 pilots before and after + 6.5 Gz,+ 7.0 Gz and + 8.0 Gz centrifuge exposures.The SAA was measured by a-amylase kit (dynamic monitoring method) and chemiluminescnet immunoassay.Results ①The SAA and cortisol levels significantly changed by different +Gz exposures (F= 17.712,3.427,P<0.01 or P<0.05).Compared with that before exposures,the SAA levels measured after +6.5 Gz,+ 7.0 Gz and +8.0 Gz exposures were significantly higher (P<0.01).The cortisol levels after +7.0 Gz and +8.0 Gz exposures were significantly higher than the baseline (P<0.05 or 0.01).The cortisol level obtained after +8.0 Gz exposure was significantly higher than that before + 6.5 Gz,+ 7.0 Gz and + 8.0 Gz centrifuge exposures (P<0.05).②Multivariate analysis showed that the aircraft type,pilot's age and flying hours had no influence on SAA and cortisol levels obtained after +Gz exposures.③ Pilots' cortisol levels were negatively correlated to the age and aircraft type of (r=-0.328,-0.694,P<0.05) but positively correlated to flying hours and +Gz level (r=0.466,0.141,P<0.05).SAA was positively correlated to +Gz level (r=0.354,P<0.01).④The levels of cortisol and SAA had less correlation either before or after +Gz exposure.Conclusions SAA elevates sensitivity with +Gz stress increase and quickly returns to baseline.So we can conclude that SAA could be a valid indicator of +Gz stress. \n \nKey words: \nAcceleration; Stress; Saliva; Alpha-amylase","PeriodicalId":9904,"journal":{"name":"中华航空航天医学杂志","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2014-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华航空航天医学杂志","FirstCategoryId":"1087","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1007-6239.2014.02.002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective To investigate the influence of +Gz acceleration on saliva a-amylase (SAA) of pilots,so as to assess the feasibility of taking SAA as an indicator of +Gz stress on pilots.Methods Saliva was collected from 47 pilots before and after + 6.5 Gz,+ 7.0 Gz and + 8.0 Gz centrifuge exposures.The SAA was measured by a-amylase kit (dynamic monitoring method) and chemiluminescnet immunoassay.Results ①The SAA and cortisol levels significantly changed by different +Gz exposures (F= 17.712,3.427,P<0.01 or P<0.05).Compared with that before exposures,the SAA levels measured after +6.5 Gz,+ 7.0 Gz and +8.0 Gz exposures were significantly higher (P<0.01).The cortisol levels after +7.0 Gz and +8.0 Gz exposures were significantly higher than the baseline (P<0.05 or 0.01).The cortisol level obtained after +8.0 Gz exposure was significantly higher than that before + 6.5 Gz,+ 7.0 Gz and + 8.0 Gz centrifuge exposures (P<0.05).②Multivariate analysis showed that the aircraft type,pilot's age and flying hours had no influence on SAA and cortisol levels obtained after +Gz exposures.③ Pilots' cortisol levels were negatively correlated to the age and aircraft type of (r=-0.328,-0.694,P<0.05) but positively correlated to flying hours and +Gz level (r=0.466,0.141,P<0.05).SAA was positively correlated to +Gz level (r=0.354,P<0.01).④The levels of cortisol and SAA had less correlation either before or after +Gz exposure.Conclusions SAA elevates sensitivity with +Gz stress increase and quickly returns to baseline.So we can conclude that SAA could be a valid indicator of +Gz stress.
Key words:
Acceleration; Stress; Saliva; Alpha-amylase
期刊介绍:
The aim of Chinese Journal of Aerospace Medicine is to combine theory and practice, improve and popularize, actively advocate a hundred flowers bloom and a hundred schools of thought contend, advocate seeking truth from facts, promote the development of the related disciplines of aerospace medicine and human efficiency, and promote the exchange and penetration of aerospace medicine and human efficiency with other biomedical and engineering specialties.
Topics of interest for Chinese Journal of Aerospace Medicine include:
-The content of the journal belongs to the discipline of special medicine and military medicine, with the characteristics of multidisciplinary synthesis and cross-penetration, and mainly reflected in the aerospace industry, aerospace flight safety and efficiency, as well as the synthesis of special medicine, preventive medicine, environmental medicine, psychology, etc.
-Military aeromedicine (Air Force, Navy and Army aeromedicine) and civil aeromedicine, with a balance of aerospace medicine are the strengths of the journal.
-The change in aerospace medicine from a focus on promoting physiological compensatory adaptations to enhancing human performance under extreme environmental conditions is what the journal is helping to promote.
-The expansion of manuscripts in high altitude medicine is also a special emphasis of the journal.