First transfemoral biologic aortic valve implantation in Slovenia

Q4 Medicine
M. Bunc, K. A. Juvan, J. Ambrožič, Š. Mušič, Bojan Kontestabile, A. Cerar, Irena Lopatič, N. Lakič, D. Zorman
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Abstract

Calcified aortic stenosis is the most frequent valvular heart disease in the Western world. It is a progressive, degenerative, atheroscleroticlike process that involves the aortic valve with increasing prevalence as the population ages. Surgical aortic valve replacement is the treatment of choice for patients with severe, symptomatic aortic stenosis, but it has limitations in old patients with high perioperative risk and in patients with comorbidities. A new method of percutanous aortic valve implantation has been developed recently. It is indicated in symptomatic patients with high perioperative risk. Case report: A case of a 83-year-old female patient with severe, symptomatic aortic valve stenosis and a high haemorrhagic risk due to vascular– ectatic changes after surgery for gastric carcinoid tumor is reported. She was refused for surgical aortic valve replacement. Transfemoral implantation of Edwards SAPIEN aortic valve was indicated. On the day after implantation the patient stood up; she improved clinically as well as objectively. Conclusions: Our case shows that there are additional therapeutic options for high-risk patients with severe aortic stenosis. Transfemoral aortic valve implantation is a procedure that does not require anaesthesia and thoracotomy. The implantation requires teamwork involving interventional cardiologist, cardio-vascular surgeon and anaesthesiologist. The real clinical value of the method is yet to be established as a result of ongoing clinical trials and in cooperation between interventional cardiologists and cardiac surgeons.
斯洛文尼亚首例经股生物主动脉瓣植入术
钙化主动脉瓣狭窄是西方世界最常见的瓣膜性心脏病。这是一种累及主动脉瓣的进行性、退行性、动脉粥样硬化样病变,随着人口年龄的增长,患病率越来越高。手术主动脉瓣置换术是严重症状性主动脉瓣狭窄患者的首选治疗方法,但在围手术期风险高的老年患者和有合并症的住院患者中存在局限性。经皮主动脉瓣植入术是近年来发展起来的一种新方法。它适用于围手术期风险高的有症状患者。病例报告:报告一例83岁女性类胃癌术后因血管扩张改变而出现严重症状性主动脉瓣狭窄及出血风险高的病例。她被拒绝进行主动脉瓣置换术。经股植入Edwards SAPIEN主动脉瓣。植入后第二天,患者站立;她在临床上和客观上都有所改善。结论:我们的病例表明,对于严重主动脉瓣狭窄的高危患者,有额外的治疗选择。经股主动脉瓣植入术不需要麻醉和开胸。植入需要介入心脏病专家、心血管外科医生和麻醉师的团队合作。该方法的真正临床价值还有待临床试验的结果以及介入心脏病专家和心脏外科医生之间的合作。
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来源期刊
CiteScore
0.30
自引率
0.00%
发文量
65
审稿时长
4-8 weeks
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