Serum levels of vitamin D, magnesium, calcium, iron, and total iron binding capacity in HIV-infected patients

Abstract

Introduction: Alterations of vitamins and minerals have been seen in patients with the human immune virus (HIV) in numerous studies. This study aimed to evaluate serum levels of vitamin D, magnesium, calcium, iron, and total iron binding capacity (TIBC) in HIV-infected patients compared with controls in western Iran. Material and methods: Ninety-eight HIV-infected prisoners and 98 healthy controls were selected for the study in 2016. Cluster of differentiation 4 (CD4) was checked in all HIV-infected patients. Age, sex, vitamin D, calcium, magnesium, iron, and TIBC were checked for each person in both groups. Results: The mean age (range) of the HIV-infected and the healthy control groups was 40.11 years (21-68 years) and 45.59 (18-85 years), respectively. Vitamin D, calcium, iron and TIBC levels were significantly different in the two groups. There was a significant correlation between calcium and iron levels and the CD4 count. Conclusions: There were significant differences in vitamin D, calcium, iron, and TIBC levels in the HIV-infected patients compared to the healthy controls. Therefore, the results show the correlation between these levels and the incidence of HIV. In addition, the significant difference between calcium and iron levels with the CD4 counts can enhance the correlation.