To Investigate the Morphologic Alterations in and Around the Optic Disc by Optical Coherence Tomography (OCT) in Eyes with Different Degree of Myopia

Abstract

Objective: To investigate the morphologic alterations in and around the optic disc by optical coherence tomography (OCT) in eyes with different degree of myopia. Methods: This prospective study included 110 myopic subjects for evaluation of Peripapillary Retinal Nerve Fiber Layer (pRNFL) pattern in myopia. Results: In our study we observed that in SE Group 1 (-3D to -6D), the average pRNFL thickness, Mean disc area and mean CD Ratio was 87.67 μm, 1.850±0.36, 0.46±0.09 while in SE Group 2 (> -6D to -10D) it was 82.56 μm, 1.89±0.23, 0.49±0.06 and in SE Group 3 (> -10D) the thickness was found to be 67.75 μm, 2.54±0.24, 0.49±0.05 respectively. This decrease in pRNFL thickness is highly statistically significant (p < 0.001) in different groups. Similar results were seen with Al Group 1,2 and 3. Conclusion: Average pRNFL thickness clearly exhibited a decreasing pattern as spherical equivalent and Axial length increases while it is not followed in all quadrants. The average disc area increases however CD ratio remains unchanged as spherical equivalent increases.