Treatment of refractory acne using selective sebaceous gland electro-thermolysis combined with non-thermal plasma

IF 1.2 4区医学 Q3 DERMATOLOGY

Journal of Cosmetic and Laser Therapy Pub Date : 2021-11-17 DOI:10.1080/14764172.2022.2050760

Xiaojin Wu, Yali Yang, Yutong Wang, Haoyu Wang, Ying Zheng, Jun Chen, Hui Xu

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引用次数: 1

Abstract

ABSTRACT Acne is one of the most common skin diseases whose disfiguring results may cause psychological problems. Despite of the various choices in the treatment of acne, new therapy with fewer complications and lower relapse rate is still in need. In this study, we aim to evaluate the clinical efficacy of a new therapy using selective sebaceous gland electro-thermolysis and non-thermal plasma (NTP) in refractory acne patients. Treatments were given at a monthly interval for three times. The last visit was set at 3 months after the third treatment. Thirty-six moderate to very severe acne patients were enrolled. All the patients got more than 50% clearance after the third treatment. The excellent response rate was 44% at 1 month after the third treatment and 50% at 3 months after the third treatment. Porphyrin and erythema values were significantly reduced after the third treatment. No irreversible complication was reported. Selective sebaceous gland electro-thermolysis combined with NTP can be a safe and effective new option in the treatment of acne.

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选择性皮脂腺电热溶解联合非热等离子体治疗难治性痤疮

痤疮是最常见的皮肤病之一，其毁容结果可引起心理问题。尽管痤疮的治疗方法多种多样，但仍需要并发症少、复发率低的新疗法。在这项研究中，我们旨在评估选择性皮脂腺电热溶解和非热等离子体(NTP)治疗难治性痤疮患者的临床疗效。治疗间隔为每月三次。最后一次访问是在第三次治疗后3个月。研究人员招募了36名中度至重度痤疮患者。第三次治疗后，所有患者的清除率均在50%以上。第三次治疗后1个月的优异有效率为44%，第三次治疗后3个月的优异有效率为50%。第三次治疗后，卟啉和红斑值明显降低。无不可逆并发症报道。选择性皮脂腺电热溶解结合NTP可以是一个安全有效的治疗痤疮的新选择。

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来源期刊

Journal of Cosmetic and Laser Therapy DERMATOLOGY-SURGERY

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues