Correlation between glycated hemoglobin and venous blood sugar in diabetic patients monitored in Abidjan

M. Absalome, C. Massara, K. Gervais, Diallo Issiagha, A. A. Alexandre, Yapo-Ake B en edicte, Ecrabey Yann Christian, Kouakou Francisk, Bene Yao Roger Esp erance, T. G. Georges
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Abstract

The aim of this study was to determine the correlation between glycated hemoglobin and blood sugar levels in diabetic subjects carried out in Abidjan. This cross-sectional study included 100 patients with diabetes monitored, for three months, for whom glycated blood glucose and hemoglobin were performed, this after informed consent of the patients. Pearson and Spearman correlation tests were used, at the 5% threshold. The patients with normal HbA1C and normal blood glucose accounted for 55.34 and 32%, respectively. A sedentary lifestyle and body mass index > 25 kg/m² were associated with a significant increase in the risk of increased blood glucose and HbA1C. The presence of a complication was associated with a 3.06-fold higher risk of high glycated hemoglobin (p= 0.0073), while blood glucose was not significantly associated with the onset of complications. Glycated hemoglobin was significantly correlated with blood glucose with a correlation coefficient of 0.4412 (p 0.0001). In multivariate analysis, hyperglycemia was significantly associated with alcohol consumption and non-compliance with antidiabetic treatment. Poor compliance was significantly associated with increased glycated hemoglobin (>7%) and tobacco consumption. The glycated hemoglobin was highly correlated with blood sugar, and was found to be a better predictor of diabetes complications than glycemia.   Key words: Diabetes mellitus, glycated hemoglobin, blood sugar, Abidjan, Cote d’Ivoire.
在阿比让监测糖尿病患者糖化血红蛋白和静脉血糖的相关性
本研究的目的是确定在阿比让进行的糖尿病受试者糖化血红蛋白和血糖水平之间的相关性。这项横断面研究包括100名糖尿病患者,监测了三个月,在患者知情同意后,对他们进行了糖化血糖和血红蛋白检测。使用Pearson和Spearman相关检验,阈值为5%。HbA1C和血糖正常的患者分别占55.34%和32%。久坐不动的生活方式和体重指数> 25 kg/m²与血糖和HbA1C升高的风险显著增加相关。并发症的出现与高糖化血红蛋白的风险增加3.06倍相关(p= 0.0073),而血糖与并发症的发生无显著相关性。糖化血红蛋白与血糖显著相关,相关系数为0.4412 (p 0.0001)。在多变量分析中,高血糖与饮酒和不遵守抗糖尿病治疗显著相关。依从性差与糖化血红蛋白升高(>7%)和烟草消费显著相关。糖化血红蛋白与血糖高度相关,比血糖更能预测糖尿病并发症。关键词:糖尿病,糖化血红蛋白,血糖,阿比让,科特迪瓦。
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