Organ Bioprinting: The Next Generation Revolution in Medical Science

M. Patel
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Abstract

The idea about lab grown organs is possibly the end of drug testing on the experimental animals or the human participants. Solution of organ shortage and the desperate ending state of organ donations worldwide can be solved. 3D Bioprinting is a revolutionary mind blowing medical technology emerged in the last few years. It involves the creation of living tissues, like bones, blood vessels, heart or skin with the help of additive manufacturing which is also known as 3D Bioprinting. Unlike other printing technology for the objects, Bioprinting not only needs living cells, they also need environment for nurturing to stay them alive, like food, water and oxygen. Nowadays, these kinds of conditions are provided by microgel, such as gelatin enriched with proteins, vitamins and many other compounds for life sustaining. Furthermore, for creating the fostering conditions and fastest efficient cell growth, scientist plant cells around 3D scaffolds which made of biodegradable polymers or collagen so that organ can able to grow in fully functional living tissue. Bioprinting is time-consuming and difficult also, but by doing proper research all problems can be solved for making organs available in transplantation process. Mass production of the organs for medical purpose likely to solve in the coming next decade. Also it is too much difficult to print the complex organs. Also if the technology available more easily, tissue engineering will become more feasible than entire organ printing. Bionic ear, synthetic skin, bladder or cornea might be the first tissues to be bio printed or completely grown in the lab on demand. These tissues having small numbers of cell types, it can be the first one for fully grown bio printed organs. After this success, bio printing of more complex organs can be done in future.
器官生物打印:医学科学的下一代革命
实验室培育器官的想法可能是对实验动物或人类参与者进行药物测试的终结。解决器官短缺和全球器官捐献的绝望状态是可以解决的。生物3D打印是近几年出现的一项革命性的医疗技术。它涉及在增材制造的帮助下创造活组织,如骨骼、血管、心脏或皮肤,也被称为3D生物打印。与其他打印技术不同,生物打印不仅需要活细胞,还需要食物、水和氧气等环境来培养活细胞。如今,这些条件是由微凝胶提供的,比如富含蛋白质、维生素和许多其他维持生命的化合物的明胶。此外,为了创造培养条件和快速高效的细胞生长,科学家们在由可生物降解聚合物或胶原蛋白制成的3D支架周围种植细胞,使器官能够在功能齐全的活组织中生长。生物打印耗时长,难度大,但通过适当的研究,所有问题都可以解决,使器官在移植过程中可用。用于医疗目的的器官的大规模生产可能在未来十年内解决。此外,打印复杂的器官也非常困难。此外,如果技术更容易获得,组织工程将比整个器官打印更可行。仿生耳朵、合成皮肤、膀胱或角膜可能是第一批生物打印或在实验室按需完全生长的组织。这些组织有少量的细胞类型,它可以是第一个完全生长的生物打印器官。在这次成功之后,未来可以进行更复杂器官的生物打印。
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