Respiratory Failure

IF 8.8 2区 医学 Q1 MEDICINE, GENERAL & INTERNAL
C. Fletcher
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引用次数: 0

Abstract

Normal respiratory function keeps the arterial blood almost fully oxygenated and the arterial carbon dioxide pressure within a narrow range, both at rest and on the most extreme exertion. We can therefore define respiratory failure in terms of arterial blood gases as 'a fall in arterial oxygen saturation or a rise in arterial carbon dioxide pressure beyond the normal range'. We must, however, exclude three factors which may cause alterations in blood gases in the absence of respiratory failure. These are: (1) Anatomical shunting of blood past the lungs as in a right-to-left shunt in the heart. (2) Metabolic alkalosis in which, when compensated, the arterial pCO2 is increased. (3) Lowering of the ambient oxygen tension, as at high altitude.
呼吸衰竭
正常的呼吸功能使动脉血几乎完全充氧,动脉二氧化碳压在一个狭窄的范围内,无论是在休息时还是在最剧烈的运动时。因此,我们可以根据动脉血气将呼吸衰竭定义为“动脉氧饱和度下降或动脉二氧化碳压升高超过正常范围”。然而,在没有呼吸衰竭的情况下,我们必须排除可能导致血气改变的三个因素。这些是:(1)血液经过肺部的解剖分流,如心脏的右至左分流。(2)代谢性碱中毒,当得到补偿时,动脉pCO2升高。(3)环境氧张力降低,如在高海拔地区。
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来源期刊
CiteScore
8.40
自引率
3.50%
发文量
107
审稿时长
6-12 weeks
期刊介绍: Since 1809, the Journal of the Royal Society of Medicine (JRSM) has been a trusted source of information in the medical field. Our publication covers a wide range of topics, including evidence-based reviews, original research papers, commentaries, and personal perspectives. As an independent scientific and educational journal, we strive to foster constructive discussions on vital clinical matters. While we are based in the UK, our articles address issues that are globally relevant and of interest to healthcare professionals worldwide.
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