Effects of prednisone on urinary proteome and disease biomarkers in a rat model

Abstract

Disease biomarkers are measurable changes associated with specific pathophysiological conditions that can be used to diagnose and monitor diseases, to predict prognoses and to reflect treatment efficiency. As a non-invasively accessible and relatively stable liquid, urine is a promising clinical sample source for biomarker discovery via proteomics approaches [1]. Recently, urinary proteomics has received increasing attention in disease biomarker research.