Functional Outcome of Percutaneous Needling Tenotomy with Autologous Platelet Rich Plasma Injection in Recalcitrant Tendinopathies

Madhan Jeyaraman, R. Ramesh, K. Chaudhari, Vikash Lakhmania, Amit Katharani, Preethi Selvaraj
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Abstract

Background: Chronic musculoskeletal diseases are the most common cause of severe long-term pain and physical disability. Tendinopathy is a difficult problem requiring lengthy management, and patients often respond poorly to treatment. Tendinopathy causes substantial morbidity during sporting or working activities. The new theory of tendon regeneration has been focused on the role of growth factors in the platelets and the development of different therapeutic strategies and protocols in the treatment of chronic tendinopathy.Objectives: To evaluate the efficacy and functional outcome of percutaneous needling tenotomy with autologous platelet rich plasma injection in recalcitrant tendinopathies.Methods: After excluding the patients who failed to satisfy the study protocol, the remaining 184 cases (achilles, patellar and rotator cuff tendinopathy) were treated with percutaneous needling tenotomy with autologous platelet rich plasma injection for recalcitrant tendinopathies. All the cases were followed up pre-procedurally and post-procedurally at the end of 1st, 6th and 12th month for pain relief and range of movements. The improvements in pain and range of movements are charted in terms of VAS and functional scoring system.Results: The statistical analysis was done for 184 cases of recalcitrant tendinopathies. All cases were followed up for 1 year. They showed a statistical improvement in pain and range of movements with p value <0.05 who received percutaneous needling tenotomy with autologous platelet rich plasma therapy. No serious adverse side effects were noted in the follow up period. Autologous PRP therapy improves the functional quality of life with a long term outcome.Conclusion: For recalcitrant tendinopathies, percutaneous needling tenotomy with autologous platelet rich plasma injection remains functionally superior as autologous PRP (Platelet Rich Plasma) is a constructive procedure by rejuvenating the degenerative tissues.
自体富血小板血浆注射经皮针刺肌腱切断术治疗顽固性肌腱病的功能效果
背景:慢性肌肉骨骼疾病是导致严重的长期疼痛和身体残疾的最常见原因。肌腱病是一个需要长期治疗的难题,患者对治疗的反应往往很差。在运动或工作活动中,肌腱病会引起严重的发病率。肌腱再生的新理论已经集中在血小板生长因子的作用和发展不同的治疗策略和方案在治疗慢性肌腱病。目的:评价经皮针刺肌腱切断术联合自体富血小板血浆注射治疗顽固性肌腱病变的疗效和功能结局。方法:排除不符合研究方案的患者后,对顽固性肌腱病变(跟腱、髌骨、肩袖肌腱病变)184例采用经皮针刺肌腱切断术联合自体富血小板血浆注射治疗。于手术前、术后1、6、12月末随访患者疼痛缓解情况及活动范围。疼痛和活动范围的改善是根据VAS和功能评分系统绘制的。结果:对184例顽固性肌腱病进行统计分析。所有病例均随访1年。经皮针刺肌腱切断术联合自体富血小板血浆治疗组疼痛和活动范围有统计学改善(p值<0.05)。随访期间未见严重不良反应。自体PRP治疗改善了长期预后的功能性生活质量。结论:对于顽固性肌腱病变,经皮针刺肌腱切断术联合自体富血小板血浆注射在功能上仍具有优势,因为自体富血小板血浆是一种修复退行性组织的有益方法。
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