Antinociceptive activity shown by Aerva javanica flowering top extract and its mechanistic evaluation

Abstract

: A grey perennial woolly tomentose shrub of Aerva javanica Burm. f. Juss. ex Schult. (Amaranthaceae), based on its folklore and traditionally usage, is needed to investigate for pharmacological potential. Therefore, as investigation of anti-nociceptive potential of the same was carried out and possible mechanism responsible for suppression of nociception was explored. Extract with hydro-alcoholic solvent (AJCE) and its ethyl acetate fraction (AJEAF) were prepared from flowering tops of A. javanica . Formalin