Clinico-epidemiological study of leprosy in a tertiary care hospital of Eastern India

N. Agrawal, Tirtha Raj Saha, J. Barua, Gautam Banerjee, Kingshuk Chatterjee, S. Halder, Prabal Samanta
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Abstract

Background: Accurate diagnosis of leprosy is of paramount importance, because delays and misdiagnosis are more common in non-endemic zones. It has a long incubation period, varied clinical presentations, and reaction states which can present in any point of lifetime, becoming more challenging for proper management of this enigmatous disease. Methods: This was conducted as an institution based cross- sectional study over a period of 12 months. 100 patients were selected. Inclusion and exclusion criteria were maintained. Data collected was checked, tabulated, statistically analysed and compared with existing literature. Results: In our study, majority, 49% belonged in age group of 41-60 yrs, only 6% were less than 20 years old. Male: female ratio was 3.34. 62% were from rural areas. Family history of Hansen was present in 5%. 6% had Histoid while 5% had pure neuritic representing least common subtypes. Most common occupations were Housewives (19%), shopkeepers (16%) and office workers (16%). 59% presented with hypoesthesia, 28% with fever. 59% belonged to borderline, 27% belonged to polar spectrum. Trophic ulcers were found in 20%, clawing of digits in 27%. Conclusions: Leprosy is still a pressing problem in our country. A considerable number of children and adolescents get affected indicating high rate of transmission in community. A comprehensive approach includes proper diagnosis, treatment, and identification of reaction patterns, prevention of disability and deformities, and implementation of rehabilitation measures.
东印度一家三级医院麻风病的临床流行病学研究
背景:麻风病的准确诊断至关重要,因为延误和误诊在非流行区更为常见。它的潜伏期长,临床表现多样,反应状态可以出现在生命的任何阶段,对这种神秘疾病的适当管理变得更具挑战性。方法:这是一项为期12个月的基于机构的横断面研究。选取100例患者。维持纳入和排除标准。对收集到的数据进行检查、制表、统计分析,并与现有文献进行比较。结果:在我们的研究中,大多数(49%)属于41-60岁年龄组,只有6%小于20岁。男女比例为3.34。62%来自农村地区。5%有汉森氏家族史。6%的人有组织病,而5%的人有纯神经炎,代表最不常见的亚型。最常见的职业是家庭主妇(19%)、店主(16%)和办公室职员(16%)。59%表现为感觉减退,28%表现为发热。59%属于边缘谱,27%属于极谱。营养性溃疡占20%,爪状指占27%。结论:麻风病在我国仍是一个亟待解决的问题。相当多的儿童和青少年受到影响,表明社区传播率很高。综合方法包括适当的诊断、治疗和识别反应模式,预防残疾和畸形,以及实施康复措施。
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