Clinical, Endoscopic, Histopathological Characteristics Of Colorectal Polyps In Adults At Gastroenterology – Endoscopy Center, Hue University Of Medicine and Pharmacy Hospital

Abstract

Background: Colorectal polyps are relatively common diseases in the group of lower gastrointestinal tract diseases. The prevalence of colorectal polyps ranges from 20 to 50%. Polyps are formed due to excessive hyperplasia of the mucosa and the malignancy rate of colorectal polyps is higher than other sites. Target: Describe some clinical, endoscopy and histopathology characteristics. Subjects: The patients aged 16 years old and older who were diagnosed colon polyps at the Center for Gastroenterology - Endoscopy at Hue University of Medicine and Pharmacy Hospital from April 1st, 2020 to April 30th, 2021. Methods: Crosssectional, retrospective description. Results: The mean age was 55.8 ± 15.7 years old, the most common age was ≥ 45 years old, male/female was 2/1. The common clinical symptoms: abdominal pain (83.6%), diarrhea (29.9%), constipation (28.4%), dysentery syndrome (13.4%), bloody stools (31.3%). The position of polyps: anus (1.5%), rectum (47.8%), sigmoid colon (40.3%), descending colon (31.3%), transverse colon (22.4%), ascending colon (28.4)%), cecum (13.4%). The proportion of patients ≥ 2 polyps (59.7%), 1 polyp (40.3%). Polyp sizes: 5 - < 10 mm (50.7%), < 5 mm (37.4%), ≥ 10 mm (11.9%). The percentage of sessile polyps was higher than that of pedunculated polyps at each locations. Histopathological types: adenomatous polyps (60.4%), hyperplastic polyps (35.4%), malignant polyps (4.2%). Polyps with dysplasia (64.6%), mild - grade dysplasia (56.3%), severe-grade dysplasia (8.3%). The differences were statistically significant between the grade of dysplasia and the polyp size groups, between the histopathology and the grade of dysplasia (p < 0.05). Conclusions: Colorectal polyps are more common in patients ≥ 45 years old, male are much more than female. Abdominal pain, bloody stools are common symptoms. Common polyp phenotypes are sessile polyps, ≥ 2 polyps, 5 - < 10 mm in size, mainly in the rectum. Adenomatous polyps are the most common histopathological type, with the high rate of dysplasia Key words: clinical, endoscopy, histopathology, colorectal polyps