Evaluation of Bone Turnover Markers in Patients with Acute and Chronic Leukemia.

IF 1.5 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Indian Journal of Clinical Biochemistry Pub Date : 2024-07-01 Epub Date: 2023-03-03 DOI:10.1007/s12291-023-01124-5

Reem A Al-Qaisi, Abdulnasser M Al-Gebori, Mohammed Hadi Munshed Alosami

引用次数: 0

Abstract

This study investigated different bone biomarkers (cross-linked carboxy-terminal telopeptide of type 1 collagen (CTX-1), pyridinoline (PYD), osteocalcin (OC), interleukin-6 receptor (IL-6R), calcium (Ca), and magnesium (Mg)) in terms of their metabolism in 4 different leukemia subtypes (ALL, AML, CLL and CML). The design was case control study with 30 controls and 60 cases of leukemia patients. Authors have reported many results regarding decrease as well as increase of specific bone biomarker under investigation with each leukemia subtype when compared to control. In addition, Authors reported correlations between each biomarker level and leukemia subtypes.

查看原文本刊更多论文

评估急性和慢性白血病患者的骨转换标志物

本研究调查了不同骨生物标志物（1型胶原交联羧基端端肽（CTX-1）、吡啶啉（PYD）、骨钙素（OC）、白细胞介素-6受体（IL-6R）、钙（Ca）和镁（Mg））在4种不同白血病亚型（ALL、AML、CLL和CML）中的代谢情况。研究设计为病例对照研究，包括 30 例对照组和 60 例白血病患者。作者们报告了许多结果，与对照组相比，每种白血病亚型所研究的特定骨生物标志物都会减少或增加。此外，作者还报告了每种生物标志物水平与白血病亚型之间的相关性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Indian Journal of Clinical Biochemistry BIOCHEMISTRY & MOLECULAR BIOLOGY-

CiteScore

4.50

自引率

4.80%

发文量

期刊介绍： The primary mission of the journal is to promote improvement in the health and well-being of community through the development and practice of clinical biochemistry and dissemination of knowledge and recent advances in this discipline among professionals, diagnostics industry, government and non-government organizations. Indian Journal of Clinical Biochemistry (IJCB) publishes peer reviewed articles that contribute to the existing knowledge in all fields of Clinical biochemistry, either experimental or theoretical, particularly deal with the applications of biochemistry, molecular biology, genetics, biotechnology, and immunology to the diagnosis, treatment, monitoring and prevention of human diseases. The articles published also include those covering the analytical and molecular diagnostic techniques, instrumentation, data processing, quality assurance and accreditation aspects of the clinical investigations in which chemistry has played a major role, or laboratory animal studies with biochemical and clinical relevance.