The Effect of Platelet Rich Plasma (PRP) Injection to the Wound Compared to PRP Jel Local Application Compared to Classic Dressing on Diabetic Foot Healing Ulcer

IF 1.7 4区 医学 Q2 SURGERY
Hassan Awas Saad, A. Yehia, G. Osman
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引用次数: 0

Abstract

Background: The goal of our work-study was to detect the net result and potency of of PRP local jnj. Dressings compared to PRP in jel to the wound for DFU healing compared to a control therapy of traditional classic dressing (PRP) also to decrease the recurrence (DFUs). Diabetic foot is a more famous and face any surgeon in his clinic or hospital. It has a new promise therapy of diabetic foot ulceration (DFU), with cellular and tissue regeneration, because of several methods in wound care management. All hope to attain good healing and hope to decrease recurrent rate. Patients and Methods: Forty-five patients with DFU were matched and grouped for (PRP) local injection dressings (n = 15), PRP jel to wound edges (n = 15), or classic dressing (n = 15) from August 2019 to March 2021. There were additional complications and ulcer recurrences were detected Ulcer or raw area healing and reduction were the primary objectives at 1; 3, 6, and 12 months. The study comprised 36 (80.0%) males and 9 (20.0%) females between the ages of 30 and 65 who had DFU for 1 to 10 years. Results: Local PRP injections improved healing 12/15 (80%) greater than local PRP jel dressings 10/15 (66.7%) and classic dressings 7/15(46.7%). However, PRP wound injection increase the healing of diabetic ulcers raw area more than PRP local jel or traditional classic dressing the healing period following local PRP injection was much shorter. At all follow-up visits, the in all the groups had similar rates of recurrence and complications. All of them had similar recurrence and variant safety. Conclusions: PRP injection is a more potent technique for treating DFU than local PRP jel administration and classic wound dressings, with slight the same recurrence. Less Amputation rates, infection rates, and discharges are all reduced with PRP injection than PRP jel than classic treatment.
富血小板血浆(PRP)注射液与PRP凝胶局部应用及经典敷料对糖尿病足溃疡愈合的影响
背景:我们的工作研究的目的是检测PRP局部jnj的净效果和效价。与PRP凝胶敷料相比,用于DFU愈合的伤口与对照治疗的传统经典敷料(PRP)相比也能减少复发(DFUs)。糖尿病足是一个更著名的,面对任何外科医生在他的诊所或医院。由于伤口护理管理的几种方法,它具有细胞和组织再生的新希望治疗糖尿病足溃疡。所有人都希望获得良好的愈合,并希望减少复发率。患者和方法:2019年8月至2021年3月,对45例DFU患者进行匹配并分组,分别使用(PRP)局部注射敷料(n = 15)、PRP凝胶创面敷料(n = 15)或经典敷料(n = 15)。有额外的并发症和溃疡复发被发现,溃疡或疮面愈合和缩小是1的主要目标;3、6、12个月。该研究包括36名(80.0%)男性和9名(20.0%)女性,年龄在30至65岁之间,患有DFU 1至10年。结果:局部PRP注射改善愈合12/15(80%),高于局部PRP凝胶敷料10/15(66.7%)和经典敷料7/15(46.7%)。然而,PRP创面注射比PRP局部凝胶或传统经典敷料更能促进糖尿病溃疡创面愈合,局部PRP注射后的愈合时间要短得多。在所有随访中,所有组的复发率和并发症发生率相似。所有患者的复发率和变异安全性相似。结论:PRP注射治疗DFU比局部给药PRP凝胶和传统创面敷料更有效,复发率低。与常规治疗相比,PRP凝胶注射组截肢率、感染率和出院率均显著降低。
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来源期刊
CiteScore
2.30
自引率
6.20%
发文量
31
审稿时长
>12 weeks
期刊介绍: ''European Surgical Research'' features original clinical and experimental papers, condensed reviews of new knowledge relevant to surgical research, and short technical notes serving the information needs of investigators in various fields of operative medicine. Coverage includes surgery, surgical pathophysiology, drug usage, and new surgical techniques. Special consideration is given to information on the use of animal models, physiological and biological methods as well as biophysical measuring and recording systems. The journal is of particular value for workers interested in pathophysiologic concepts, new techniques and in how these can be introduced into clinical work or applied when critical decisions are made concerning the use of new procedures or drugs.
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