Steve Konrad Williams , Jean J.M.C.H. de la Rosette , Jaime Landman , Francis Xavier Keeley Jr.
{"title":"Cryoablation of Small Renal Tumors","authors":"Steve Konrad Williams , Jean J.M.C.H. de la Rosette , Jaime Landman , Francis Xavier Keeley Jr.","doi":"10.1016/j.eeus.2007.05.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>To review the worldwide experience with cryoablation of small renal tumors.</p></div><div><h3>Methods</h3><p><span>A systematic review<span> was made of all English language publications on cryoablation of renal tumors as well as partial nephrectomy, </span></span>radiofrequency ablation<span> and high intensity focused ultrasound published prior to September 2006. The literature was reviewed and the findings analyzed.</span></p></div><div><h3>Results</h3><p>Data from basic science and clinical trials<span> supports renal<span> cryoablation as a safe and effective method for treatment of small renal tumors. Clinical studies document less peri- and post-operative morbidity than laparoscopic partial nephrectomy. Basic science and clinical studies suggest superior efficacy with cryoablation as compared to radiofrequency ablation. Longer follow-up is needed before its true efficacy can be established.</span></span></p></div><div><h3>Conclusion</h3><p>Laparoscopic renal cryoablation, though evolving, appears to be a reasonable alternative for the treatment of small renal tumors in selected patients. Meticulous long-term clinical and radiologic follow-up will be critical for determining local recurrence and cancer-free survival rates, to establish the ultimate role of renal cryoablation in the management of small renal tumors.</p></div>","PeriodicalId":100386,"journal":{"name":"EAU-EBU Update Series","volume":"5 5","pages":"Pages 206-218"},"PeriodicalIF":0.0000,"publicationDate":"2007-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.eeus.2007.05.001","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"EAU-EBU Update Series","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1871259207000329","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2007/5/22 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Objectives
To review the worldwide experience with cryoablation of small renal tumors.
Methods
A systematic review was made of all English language publications on cryoablation of renal tumors as well as partial nephrectomy, radiofrequency ablation and high intensity focused ultrasound published prior to September 2006. The literature was reviewed and the findings analyzed.
Results
Data from basic science and clinical trials supports renal cryoablation as a safe and effective method for treatment of small renal tumors. Clinical studies document less peri- and post-operative morbidity than laparoscopic partial nephrectomy. Basic science and clinical studies suggest superior efficacy with cryoablation as compared to radiofrequency ablation. Longer follow-up is needed before its true efficacy can be established.
Conclusion
Laparoscopic renal cryoablation, though evolving, appears to be a reasonable alternative for the treatment of small renal tumors in selected patients. Meticulous long-term clinical and radiologic follow-up will be critical for determining local recurrence and cancer-free survival rates, to establish the ultimate role of renal cryoablation in the management of small renal tumors.