Cryoablation of Small Renal Tumors

EAU-EBU Update Series Pub Date : 2007-10-01 Epub Date: 2007-05-22 DOI:10.1016/j.eeus.2007.05.001
Steve Konrad Williams , Jean J.M.C.H. de la Rosette , Jaime Landman , Francis Xavier Keeley Jr.
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引用次数: 7

Abstract

Objectives

To review the worldwide experience with cryoablation of small renal tumors.

Methods

A systematic review was made of all English language publications on cryoablation of renal tumors as well as partial nephrectomy, radiofrequency ablation and high intensity focused ultrasound published prior to September 2006. The literature was reviewed and the findings analyzed.

Results

Data from basic science and clinical trials supports renal cryoablation as a safe and effective method for treatment of small renal tumors. Clinical studies document less peri- and post-operative morbidity than laparoscopic partial nephrectomy. Basic science and clinical studies suggest superior efficacy with cryoablation as compared to radiofrequency ablation. Longer follow-up is needed before its true efficacy can be established.

Conclusion

Laparoscopic renal cryoablation, though evolving, appears to be a reasonable alternative for the treatment of small renal tumors in selected patients. Meticulous long-term clinical and radiologic follow-up will be critical for determining local recurrence and cancer-free survival rates, to establish the ultimate role of renal cryoablation in the management of small renal tumors.

肾小肿瘤的冷冻消融
目的总结国内外肾小肿瘤冷冻消融治疗的经验。方法系统回顾2006年9月以前发表的有关肾肿瘤冷冻消融、部分肾切除术、射频消融和高强度聚焦超声的英文文献。回顾文献并分析研究结果。结果基础科学和临床试验数据支持肾冷冻消融术是一种安全有效的治疗肾小肿瘤的方法。临床研究表明,腹腔镜部分肾切除术的围手术期和术后发病率较腹腔镜部分肾切除术低。基础科学和临床研究表明,与射频消融相比,冷冻消融的疗效更好。需要更长时间的随访才能确定其真正疗效。结论腹腔镜肾冷冻消融术虽然在不断发展,但在特定的患者中,似乎是一种治疗小肾肿瘤的合理选择。细致的长期临床和放射学随访对于确定局部复发率和无癌生存率至关重要,从而确定肾冷冻消融在小肾肿瘤治疗中的最终作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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