A Nationwide Study of Breast Cancer Histopathology in Cameroon (Central Africa)

Z. Sando, J. Fouogue, J. Kemfang, F. Y. Fouelifack
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引用次数: 2

Abstract

Background and objectives: Breast cancer is the commonest cancer in Africa. Like other countries in that continent, Cameroon has very week pathology and health information services. This study was conducted to determine the histopathologic features of breast cancer all over Cameroon.Methods: The study was retrospective and cross-sectional. Data were collected in the 10 regional hospitals and in national referral hospitals. We included complete files of patients diagnosed with breast cancer from January 1, 2008 to December 31, 2015. Doubloons were avoided for patients seen both at regional and national hospitals. Files with conflicting pathology results were excluded.Results: Of the 1666 files included, 180 (12.6%) with conflicting pathology results were excluded and1486 cases were analyzed. Mean age was 47.9 years (range 17-91 years).Ethnic groups from 3 regions out of 10 accounted for 78.1% of patients. 82.3% of cases were diagnosed in the two regions main towns of the country. Diagnosis was late, with 97.5% of patients already presenting symtpoms. Histopathological analysis was performed for 1371 (92.3%) of cases. Pathology specimens were mainly biopsies (79.4%). All male breast cancers (15 cases) and 87.7% of female cases were ductal carcinoma. Grade 2 of Scarff-Bloom-Richardson’s classification was the most frequent (51.1%) followed by Grade 3 (303%).Discussion: Ethnicity seems to have an influence on breast cancer distribution in Cameroon. Pathological diagnosis is mainly done on biopsies and ductal carcinoma is the most frequent type of breast cancer in the country. Pathology services should be evenly distributed around the country.
喀麦隆(中非)全国乳腺癌组织病理学研究
背景和目的:乳腺癌是非洲最常见的癌症。像非洲大陆的其他国家一样,喀麦隆每周都有病理和健康信息服务。本研究旨在确定喀麦隆各地乳腺癌的组织病理学特征。方法:采用回顾性和横断面研究。在10个地区医院和国家转诊医院收集数据。我们纳入了2008年1月1日至2015年12月31日诊断为乳腺癌的患者的完整档案。在地区和国家医院就诊的病人都避免使用杜布隆。排除病理结果不一致的文件。结果:在纳入的1666份文献中,排除了180份(12.6%)病理结果不一致的文献,分析了1486例病例。平均年龄47.9岁(17-91岁)。10个地区中有3个民族占78.1%。82.3%的病例在该国两个地区的主要城镇得到诊断。诊断较晚,97.5%的患者已经出现症状。1371例(92.3%)进行了组织病理学分析。病理标本以活检为主(79.4%)。所有男性乳腺癌(15例)和87.7%的女性乳腺癌为导管癌。Scarff-Bloom-Richardson分类的2级最常见(51.1%),其次是3级(303%)。讨论:种族似乎对喀麦隆的乳腺癌分布有影响。病理诊断主要通过活检完成,导管癌是该国最常见的乳腺癌类型。病理服务应在全国均匀分布。
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