Achillea millefolium L. subsp. millefolium essential oil’s antifungal effect

European Journal of Biological Research Pub Date : 2018-08-16 DOI:10.5281/ZENODO.1346338

Sinem Aydın, E. Sevindik

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引用次数: 7

Abstract

This study was carried out with the aim of determining the antifungal effect of the essential oil isolated from Achillea millefolium subsp. millefolium plant against pathogenic fungi. In order to test the antifungal effect of the oil, an analysis was conducted on a total of 4 pathogen fungi which included Candida albicans, Candida tropicalis, Candida parapsilosis and Saccharomyces cerevisiae, and the effect of the essential oil on the growth of these fungi was investigated. The essential oil of A. millefolium ssp. millefolium had varying degrees of effect on the tested fungi. The highest antifungal effect was found against S. cerevisiae; whereas the lowest antifungal effect was found against C. parapsilosis. Nystatin showed a higher activity than the essential oil of A. millefolium subsp. millefolium against the tested fungi. MIC values of the essential oil against the tested fungi ranged from 1.25 μl/ml to 10 μl/ml. The results obtained indicate that essential oil of A. millefolium subsp. millefolium can be used as an alternative to antifungal agents such as amphotericin, ketoconazole, and fluconazole. DOI: http://dx.doi.org/10.5281/zenodo.1346338

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千叶水蛭亚属。千叶精油的抗真菌作用

本实验旨在研究千年阿喀琉叶挥发油的抑菌作用。千叶植物抗病原真菌。为了检验精油的抑菌作用，对白色念珠菌、热带念珠菌、假丝酵母菌和酿酒酵母菌共4种病原菌进行了分析，并考察了精油对这些真菌生长的影响。千叶草精油。千叶对被试真菌有不同程度的影响。对酿酒葡萄球菌的抑菌效果最好;抗真菌效果最低。制霉菌素活性高于千叶草挥发油。千叶对抗测试真菌。精油对真菌的MIC值为1.25 μl/ml ~ 10 μl/ml。实验结果表明，千叶草挥发油具有明显的抗氧化活性。千叶可作为抗真菌剂的替代品，如两性霉素、酮康唑和氟康唑。DOI: http://dx.doi.org/10.5281/zenodo.1346338

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European Journal of Biological Research

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