Variation in hepatic segmental portal venous pulsed wave Doppler flow distribution in patients with NAFLD: A pilot study.

Annals of the ICRP Pub Date : 2023-11-01 Epub Date: 2023-03-22 DOI:10.1177/1742271X231154862
Ashish Verma, Ishan Kumar, Manish Indal, Sunit Shukla, Pramod Kumar Singh, Ram Chandra Shukla
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引用次数: 0

Abstract

Purpose: To evaluate the segmental variations in portal venous pulsed wave colour Doppler flow velocity in patients with moderate to severe non-alcoholic fatty liver disease in comparison with healthy controls.

Materials and methods: In this prospective, observational, case-control study, the maximum velocity of all the segmental branches of portal vein were evaluated on colour Doppler in patients with moderate to severe non-alcoholic fatty liver disease, and the values were compared between three groups (1) Healthy controls (n = 30), (2) non-alcoholic fatty liver disease group, that is moderate to severe fatty liver without features of portal hypertension (n = 32) and (3) non-alcoholic steatohepatitis-portal hypertension group, that is those non-alcoholic fatty liver disease patients with features of portal hypertension (n = 13).

Results: Compared to controls, non-alcoholic fatty liver disease group showed a lower velocity in all the eight segments of liver. The ratio of segment 2 to segment 7 peak portal vein maximum velocity was significantly higher in non-alcoholic fatty liver disease (1.03 ± 0.21) compared to controls (0.90 ± 0.17) and even higher in non-alcoholic steatohepatitis-Portal hypertension group (1.83 ± 0.40) with p value of 0.003.

Conclusion: Our study demonstrates the occurrence of flow redistribution occurring in cases of non-alcoholic fatty liver disease patients with the left lobe receiving higher portal venous flow. This flow redistribution was even more pronounced in a subset of non-alcoholic fatty liver disease patients who developed features of portal hypertension.

非酒精性脂肪肝患者肝段门静脉脉冲波多普勒血流分布的变化:一项试验性研究。
目的:与健康对照组相比,评估中重度非酒精性脂肪肝患者门静脉脉冲波彩色多普勒流速的节段变化:在这项前瞻性、观察性、病例对照研究中,用彩色多普勒评估了中重度非酒精性脂肪肝患者门静脉各节段分支的最大流速,并在三组之间进行了比较:(1)健康对照组(n = 30)、(3)非酒精性脂肪性肝炎-门静脉高压症组,即具有门静脉高压症特征的非酒精性脂肪肝患者(13 人)。研究结果与对照组相比,非酒精性脂肪肝组患者肝脏八个节段的速度均较低。与对照组(0.90 ± 0.17)相比,非酒精性脂肪肝患者第 2 节段与第 7 节段门静脉峰值最大速度之比(1.03 ± 0.21)明显升高,而非酒精性脂肪性肝炎-门静脉高压组更高(1.83 ± 0.40),P 值为 0.003:我们的研究表明,非酒精性脂肪肝患者左叶门静脉血流较高时,会出现血流再分布。在出现门静脉高压特征的非酒精性脂肪肝患者中,这种血流再分布现象更为明显。
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来源期刊
Annals of the ICRP
Annals of the ICRP Medicine-Public Health, Environmental and Occupational Health
CiteScore
4.10
自引率
0.00%
发文量
3
期刊介绍: The International Commission on Radiological Protection was founded in 1928 to advance for the public benefit the science of radiological protection. The ICRP provides recommendations and guidance on protection against the risks associated with ionising radiation, from artificial sources as widely used in medicine, general industry and nuclear enterprises, and from naturally occurring sources. These reports and recommendations are published six times each year on behalf of the ICRP as the journal Annals of the ICRP. Each issue provides in-depth coverage of a specific subject area.
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