Urinary Markers for Detecting Bladder Cancer

EAU Update Series Pub Date : 2003-06-01 Epub Date: 2003-05-31 DOI:10.1016/S1570-9124(03)00022-9
Martina Tinzl, Michael Marberger
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引用次数: 22

Abstract

Cystoscopy and urinary cytology have been the cornerstone of superficial bladder cancer diagnosis and monitoring for decades. Replacing cystoscopies by simple urinary markers is an ideal scenario, but until now, despite extensive investigations, very few tests meet the standards in terms of sensitivity and specificity for replacing the combination cystoscopy + cytology.

The present article reviews the place and effectiveness of both cell-bound and urine-bound tests in the diagnosis and follow-up of bladder cancer. None of the currently available urinary markers can replace cystoscopy at present but these tests might be useful for follow-up of bladder tumor patients.

检测膀胱癌的尿液标志物
几十年来,膀胱镜检查和尿细胞学检查一直是浅表膀胱癌诊断和监测的基础。用简单的尿液标记物代替膀胱镜检查是一种理想的情况,但到目前为止,尽管进行了广泛的研究,很少有测试在敏感性和特异性方面符合标准,可以代替膀胱镜检查和细胞学检查的组合。本文综述了细胞结合试验和尿结合试验在膀胱癌诊断和随访中的地位和有效性。目前还没有一种尿液标志物可以代替膀胱镜检查,但这些检查可能对膀胱肿瘤患者的随访有用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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