Lemierre’s Syndrome: A Case Report of a Child With Partial Treatment of Streptococcal Pharyngitis

J. Pryor, Priya G. Sharma, Rachel A. Reedy
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引用次数: 1

Abstract

Lemierre’s syndrome (LS) is a complication of acute oropharyngeal infections leading to septic thrombophlebitis of the internal jugular vein. Since initial discovery, the incidence of LS has decreased due to development of modern antibiotics. In our case report, a child with partially treated streptococcal pharyngitis presented with neck pain, neck swelling and limited range of motion of her neck. Although the patient was well appearing and with an atypical presentation of LS, the diagnosis of LS was confirmed with a computed tomography (CT). As a result, appropriate treatment was quickly initiated to prevent further complication and provide a favorable outcome for the patient. Typical presenting symptoms of LS include fever, dysphagia, neck pain and arthralgia that should lead to the ordering of appropriate laboratory studies and imaging. CT imaging aids in both the diagnosis and management of LS. The use of anticoagulation therapy remains controversial in the management of LS. In addition, there are no generalized guidelines for the treatment of LS, but antibiotic therapy directed at anaerobic coverage can significantly reduce morbidity and mortality in otherwise healthy children. Due to potentially fatal complications, it is crucial to keep LS on the differential diagnosis list in pediatric patients with fever, neck pain, neck swelling, or dysphagia in the week following an oropharyngeal infection. Int J Clin Pediatr. 2020;9(1):4-8 doi: https://doi.org/10.14740/ijcp347
Lemierre综合征:儿童部分治疗链球菌性咽炎1例报告
Lemierre综合征(LS)是急性口咽感染导致颈内静脉脓毒性血栓性静脉炎的并发症。自最初发现以来,由于现代抗生素的发展,LS的发病率已经下降。在我们的病例报告中,一名患有部分治疗的链球菌性咽炎的儿童表现为颈部疼痛,颈部肿胀和颈部活动范围有限。虽然患者表现良好,但LS的表现不典型,但通过计算机断层扫描(CT)证实了LS的诊断。因此,迅速开始适当的治疗,以防止进一步的并发症,并为患者提供良好的结果。LS的典型症状包括发热、吞咽困难、颈部疼痛和关节痛,应进行适当的实验室检查和影像学检查。CT成像有助于LS的诊断和治疗。在LS的治疗中,抗凝治疗的使用仍然存在争议。此外,对于LS的治疗没有通用的指南,但是针对无氧覆盖的抗生素治疗可以显著降低其他健康儿童的发病率和死亡率。由于潜在的致命并发症,在口咽感染后一周内出现发烧、颈部疼痛、颈部肿胀或吞咽困难的儿科患者,将LS列入鉴别诊断清单至关重要。国际儿科临床杂志,2020;9(1):4-8 doi: https://doi.org/10.14740/ijcp347
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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