Ocular Manifestations of Stevens-Johnson Syndrome

Daniar Indah Suryowati, Ratna Doemillah
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Abstract

The purpose of this case report was to have a further study of the proper management of ocular manifestations caused by Stevens-Johnson Syndrome, which aims to minimize the chances of complications. This case report will discuss the ocular manifestations of Stevens-Johnson syndrome. A case report. A 4 years old girl with the problem on admission was the adhesion of her membranes layer (conjunctiva) and eyelid on both of her eyes. The patient’s family also gave additional information on the patient’s eyes problem: pain on both her eyes, tearing, discharge which came out frequently from her eyes, and a white spot in the black section of her eyes. The fluorescein test revealed a positive result, with conjunctival hyperemia. The case was treated as symblepharon and corneal erosion post Stevens-Johnson syndrome, for temporary treatment using artificial tears and antibiotic eye ointment. Ocular manifestations occur in a significant number of patients, and the most severe form of Stevens-Johnson syndrome occurs in those at the end of the spectrum. The acute phase of the disease is characterized primarily by eyelid involvement. The lids are typically swollen and erythematous. Soon after that, or coincident with this, the conjunctiva is inflamed. Conjunctivitis frequently parallels the skin findings, with bullae formation and eruption. Membrane or pseudo-membrane formation then occurs. The healing process can result in cicatricial changes, including symblepharon, ankyloblepharon, eyelid margin rotation, severe dry eye, and conjunctivilization of the cornea.
史蒂文斯-约翰逊综合征的眼部表现
本病例报告的目的是进一步探讨史蒂文斯-约翰逊综合征引起的眼部表现的正确处理,以尽量减少并发症的发生。本病例报告将讨论史蒂文斯-约翰逊综合征的眼部表现。一份病例报告。一名4岁女孩入院时的问题是她的双眼膜层(结膜)和眼睑粘连。患者家属还提供了关于患者眼睛问题的额外信息:双眼疼痛,流泪,眼睛经常流出分泌物,眼睛黑色部分有白斑。荧光素试验显示阳性,结膜充血。病例以史蒂文斯-约翰逊综合征后睑粘连和角膜糜烂治疗,暂时使用人工泪液和抗生素眼膏治疗。许多患者都有眼部表现,史蒂文斯-约翰逊综合征最严重的形式发生在谱系的末端。本病急性期主要表现为累及眼睑。眼睑通常是肿胀和红斑。不久之后,或者与此同时,结膜开始发炎。结膜炎常与皮肤相似,伴有大疱形成和爆发。然后形成膜或伪膜。愈合过程可导致瘢痕性改变,包括睑粘连、强直性睑粘连、睑缘旋转、严重干眼和角膜结膜炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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