Use of internal thoracic artery as a conduit protects coronary artery in the long-term period after coronary artery bypass graft surgery

A. Frolov, N. Zagorodnikov, R. Tarasov, E. V. Grigoriev, S. Ivanov, L. Barbarash
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Abstract

Aim. To assess whether the internal thoracic artery (ITA) is able to protect coronary artery (CA) after coronary artery bypass graft (CABG) surgery.Material and Methods. Having performed coronary angiography in the long term after CABG surgery, we evaluated 102 angiograms by visual analysis and using Gensini score and SYNTAX score. Using these parameters, we investigated the association of internal thoracic artery and saphenous vein grafts with anatomy and pathology of the coronary artery.Results. Calculation of Gensini score revealed that use of ITA grafts was associated with mild coronary atherosclerosis [4 (0; 17)] as compared with SV grafts [32 (2 ; 32)]. Relative increase of atherosclerotic burden in the coronary artery was 21.05% for the ITA grafts and 102.87% for the SV grafts. Lesion growth rate was significantly higher after using SV grafts than in case with ITA grafts (p = 0.0002)Conclusion. ITA grafts reduce progression of atherosclerosis in bypassed coronary arteries in comparison with SV grafts.
在冠状动脉搭桥术后,胸内动脉作为导管对冠状动脉的长期保护作用
的目标。目的探讨胸内动脉(ITA)在冠状动脉搭桥术(CABG)术后对冠状动脉(CA)的保护作用。材料和方法。在CABG术后长期进行冠状动脉造影后,我们通过视觉分析并使用Gensini评分和SYNTAX评分对102张血管造影图像进行评估。利用这些参数,我们研究了胸内动脉和隐静脉移植与冠状动脉解剖和病理的关系。Gensini评分显示ITA移植与轻度冠状动脉粥样硬化相关[4 (0;17)]与SV移植物相比[32 (2;32)]。ITA组冠脉动脉粥样硬化负荷增加21.05%,SV组冠脉动脉粥样硬化负荷增加102.87%。SV移植后病变生长速度明显高于ITA移植(p = 0.0002)。与SV移植相比,ITA移植可减少旁路冠状动脉动脉粥样硬化的进展。
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