Cause-Specific Mortality among HIV-Infected Persons in One Medical Center, Tehran, Iran

Zahra Arab-Mazar, Fahimeh Hadavand, P. Tabarsi, F. Abbasi
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Abstract

Background: Human immunodeficiency virus (HIV) is one of the major infectious agents, which has important role in the public health challenges, which have affected the world's economic and social situation recent decades. During the last decades, millions of people died due to HIV infection worldwide. However, data remain limited on the causes of death among HIV-infected in Iranian population. The aim of the present study was to assess the cause specific death among HIV positive inpatient persons in Iran. M aterials and Methods: This surveillance was conducted on inpatient HIV positive admissions at Masih Daneshvari Hospital, Tehran, Iran during October 2016 and April 2017.All patient’s data were collected via abstraction form, which were ascertained, from medical records and from written logbooks that were kept by the nursing staff on the ward. The data of each admission was recorded from the medical reports at the time of admission and upon discharge. All laboratory data were collected and recorded separately. R es ults: Fifty persons were diagnosed as HIV-infected patients, of which 58% of them were classified as AIDS patients. Our findings indicated that the cause of hospitalization were pulmonary 54%, neurological 20%, gastrointestinal 16%, and dermal 10% complications. Overall, 21 patients (42%) were diagnosed with pulmonary tuberculosis, of which one patient died from tuberculosis complications. Four patients died during the study period. C onclusion: In conclusion, early treatment and/or early use of ART can be improved outcomes. Therefore, early HIV testing and early ART use play important role in mortality reduction among eligible persons.
伊朗德黑兰一家医疗中心艾滋病毒感染者的病因特异性死亡率
背景:人类免疫缺陷病毒(HIV)是主要的传染性病原体之一,在公共卫生挑战中发挥着重要作用,近几十年来影响着世界经济和社会形势。在过去的几十年中,全世界有数百万人死于艾滋病毒感染。然而,关于伊朗艾滋病毒感染者死亡原因的数据仍然有限。本研究的目的是评估伊朗艾滋病毒阳性住院患者的死因特异性死亡。材料和方法:对2016年10月至2017年4月在伊朗德黑兰Masih Daneshvari医院住院的HIV阳性患者进行监测。所有患者资料均通过抽取表格收集,抽取表格由病区护理人员保存的病历和书面日志中确定。每次入院的数据都记录在入院时和出院时的医疗报告中。所有实验室数据均单独收集和记录。结果:50人被诊断为hiv感染者,其中58%的人被归为艾滋病患者。我们的研究结果表明,住院的原因是肺部并发症占54%,神经系统并发症占20%,胃肠道并发症占16%,皮肤并发症占10%。总体而言,21名患者(42%)被诊断为肺结核,其中1名患者死于肺结核并发症。4名患者在研究期间死亡。结论:总之,早期治疗和/或早期使用抗逆转录病毒治疗可以改善预后。因此,早期艾滋病毒检测和早期使用抗逆转录病毒治疗在降低符合条件的人的死亡率方面发挥着重要作用。
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