FGF2- Mediated Programming of Macrophages: A Novel Target for Cancer Therapy

J. Im, R. Muschel
{"title":"FGF2- Mediated Programming of Macrophages: A Novel Target for Cancer Therapy","authors":"J. Im, R. Muschel","doi":"10.35248/2157-2518.21.12.362","DOIUrl":null,"url":null,"abstract":"Macrophages are present in essentially all cancers. In general these Tumor Associated Macrophages (TAMs) facilitate the growth of cancers, suppress the anti-cancer immune response and promote angiogenesis. Because of these tumor promoting actions, targeting macrophages is a promising, but mainly unrealized strategy for cancer therapy.","PeriodicalId":15209,"journal":{"name":"Journal of carcinogenesis & mutagenesis","volume":"19 1","pages":"1-3"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of carcinogenesis & mutagenesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2157-2518.21.12.362","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Macrophages are present in essentially all cancers. In general these Tumor Associated Macrophages (TAMs) facilitate the growth of cancers, suppress the anti-cancer immune response and promote angiogenesis. Because of these tumor promoting actions, targeting macrophages is a promising, but mainly unrealized strategy for cancer therapy.
巨噬细胞FGF2介导的编程:癌症治疗的新靶点
巨噬细胞基本上存在于所有的癌症中。一般来说,这些肿瘤相关巨噬细胞(Tumor Associated Macrophages, tam)促进肿瘤生长,抑制抗癌免疫反应,促进血管生成。由于这些肿瘤促进作用,靶向巨噬细胞是一种很有前途的癌症治疗策略,但主要尚未实现。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信