Lipid-lowering therapy of cardiovascular diseases (literature review)

Abstract

Literature data on the pathogenesis of atherosclerosis, the use of statins, ezetimibe and inhibitors of subtilisin / kexin type 9 proprotein convertase monoclonal antibodies (PCSK9) in the prevention and treatment of cardiovascular diseases have been presented.Objective - to systematize current data on the pathogenesis of atherosclerosis, the effectiveness of lipid-lowering therapy of cardiovascular diseases.Conclusion. To date, the role of dyslipidemia and inflammation in the pathogenesis of atherosclerosis, the effectiveness of statins, ezetimibe and PCSK9 inhibitors in the prevention and treatment of cardiovascular diseases have been established.