Development of high-resolution intraluminal and intravascular MRI probe using microfabrication on cylindrical substrates

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS) Pub Date : 2007-01-01 DOI:10.1109/MEMSYS.2007.4433065

S. Goto, T. Matsunaga, Y. Matsuoka, K. Kuroda, M. Esashi, Y. Haga

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引用次数: 19

Abstract

The objective of this study is development of high-resolution intraluminal and intravascular MRI probe using microfabrication on cylindrical substrates. MRI holds promise for in vivo characterization due to its potential for obtaining high-resolution images and its sensitivity to the compositional characteristics of lesion. By placing a receive coil in the human body, NMR signals from the tissue surrounding the coil can be detected sensitively and the method enables in vivo high-resolution imaging (high spatial resolution and high spectroscopic resolution). The preferable receive coil has homogeneous RF receptivity around the probe and high-SNR. Novel coil designs and/or multi-coil have capabilities to meet these demands. To connect the tuning/matching circuit and amplifier circuit near the coil is needed to improve SNR of the system. Microfabrication on cylindrical substrate is one of methods for fabricating arbitrary coil pattern and the tuning/matching circuit on the tube with small diameters. Using a maskless lithography technique, solenoid coil, tilted coil and saddle shaped coil have been fabricated on glass tube with 2 mm O.D.. Imaging test of the coils were performed on 3 T MRI in a 2% agar phantom.

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高分辨率腔内和血管内MRI探针在圆柱形基板上的微加工

本研究的目的是开发高分辨率腔内和血管内MRI探针，在圆柱形衬底上使用微加工。由于MRI具有获得高分辨率图像的潜力以及对病变成分特征的敏感性，因此它有望用于体内表征。通过在人体中放置一个接收线圈，可以灵敏地检测到来自线圈周围组织的核磁共振信号，并且该方法可以实现体内高分辨率成像(高空间分辨率和高光谱分辨率)。优选的接收线圈在探头周围具有均匀的射频接受度和高信噪比。新颖的线圈设计和/或多线圈有能力满足这些要求。为了提高系统的信噪比，需要在线圈附近连接调谐/匹配电路和放大电路。圆柱基板微加工是在小直径管上制作任意线圈图案和调谐/匹配电路的方法之一。采用无掩模光刻技术，电磁线圈，倾斜线圈和鞍形线圈已制作在玻璃管与2mm外径。在3t MRI上对线圈进行2%琼脂幻影成像测试。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

2007 IEEE 20th International Conference on Micro Electro Mechanical Systems (MEMS)

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