{"title":"Creation of Nanorobots: Both State-of-the-Science and State-of-the-Art","authors":"P. Hassanzadeh, F. Atyabi, R. Dinarvand","doi":"10.14748/BMR.V27.2109","DOIUrl":null,"url":null,"abstract":"Over the last decade, remarkable achievements in nanofabrication technology has led to the development of hybrid intelligent systems including the nanomechanical devices powered by the chemical energy sources or biomolecular motors. In this context, nanorobotics has emerged as a highly-advanced technology for designing the fully functional smart devices or robots at nano scale. Development of these highly-controlled and functional nanostructures for sensing, information processing, signaling, and actuation may provide remarkable breakthroughs in medicine such as the improved imaging or targeted therapeutic interventions. Besides the detection and destroying the toxic materials and ecosystem restoration, the stimuli-responsive nanorobots may be used for the diagnosis or treatment of cardiac disorders, traumatic injuries, diabetes, and bacterial or viral infections. These molecular tools with nanoscale resolution facilitates early diagnosis in cancer and precise localization of anticancer agents leading to the minimal side effects. Nanorobots may easily traverse the human body and repair the cells or assist an improper functioning organ. These tiny devices integrated with wireless locomotion, external or internal power supply, artificial intelligence, and smart sensors may also be used for targeted delivery of genes or drugs into the single cells or tissues, tele-operation, or patient monitoring. Indeed, development of the medical nanorobots with a wide range of capabilities is a proof of concept and art in modern science and a breakthrough in nanotechnology which has been highlighted in the present manuscript.","PeriodicalId":8906,"journal":{"name":"Biomedical Reviews","volume":"101 2 1","pages":"19-26"},"PeriodicalIF":0.0000,"publicationDate":"2017-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"18","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Reviews","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14748/BMR.V27.2109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 18
Abstract
Over the last decade, remarkable achievements in nanofabrication technology has led to the development of hybrid intelligent systems including the nanomechanical devices powered by the chemical energy sources or biomolecular motors. In this context, nanorobotics has emerged as a highly-advanced technology for designing the fully functional smart devices or robots at nano scale. Development of these highly-controlled and functional nanostructures for sensing, information processing, signaling, and actuation may provide remarkable breakthroughs in medicine such as the improved imaging or targeted therapeutic interventions. Besides the detection and destroying the toxic materials and ecosystem restoration, the stimuli-responsive nanorobots may be used for the diagnosis or treatment of cardiac disorders, traumatic injuries, diabetes, and bacterial or viral infections. These molecular tools with nanoscale resolution facilitates early diagnosis in cancer and precise localization of anticancer agents leading to the minimal side effects. Nanorobots may easily traverse the human body and repair the cells or assist an improper functioning organ. These tiny devices integrated with wireless locomotion, external or internal power supply, artificial intelligence, and smart sensors may also be used for targeted delivery of genes or drugs into the single cells or tissues, tele-operation, or patient monitoring. Indeed, development of the medical nanorobots with a wide range of capabilities is a proof of concept and art in modern science and a breakthrough in nanotechnology which has been highlighted in the present manuscript.