Post- COVID-19 multisystem inflammatory syndrome in children

V. Dalal, Rincy Reji, R. Jain, Sreelakshmi S Mohandas, Prasad N Bali
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Abstract

COVID-19 is a severe acute respiratory infection affecting worldwide population. There are many cases of complications after the COVID exposure occurring nowadays. One among is Post-COVID-19 Multisystem Inflammatory Syndrome in Children (MIS-C). As per CDC report till March 1, 2021, 2617 cases of MIS-C were meeting the definite case criteria and among 33 death cases were reported. Here we report a case of COVID-19 associated Multi-system inflammatory syndrome in a child (MIS-C) interpreted with WHO case definition criteria. The patient was a 7-year-old boy, with initial presentation of moderate fever, non-itchy red blanching rashes, breathlessness, later progressed to cardiogenic shock accompanied by positive SARS-CoV-2 antigen result. The emergency cardiogenic shock treatment protocol was followed with initial stabilization and resuscitation strategy. He was successfully managed by three days of IV Immunoglobulin 2g/kgand Methylprednisolone 2mg/kg/day therapy along with other supportive treatments. The patient was discharged after 20 days of hospital stay with improved health condition. Our case report will strengthen the exposure-outcome relations between the coronavirus infection and MIS-C, moreover the strategies carried out in our case will be a future direction for the effective management of MIS-C.
儿童COVID-19后多系统炎症综合征
COVID-19是一种影响全球人口的严重急性呼吸道感染。目前,感染新冠病毒后出现并发症的病例很多。其中之一是covid -19后儿童多系统炎症综合征(MIS-C)。根据疾病预防控制中心截至2021年3月1日的报告,2617例misc病例符合明确的病例标准,在33例死亡病例中报告。在这里,我们报告了一例儿童COVID-19相关多系统炎症综合征(MIS-C),根据世卫组织病例定义标准进行解释。患者为一名7岁男孩,最初表现为中度发热,无发痒红色漂疹,呼吸困难,后来进展为心源性休克并伴有SARS-CoV-2抗原结果阳性。急诊心源性休克治疗方案遵循初步稳定和复苏策略。通过静脉注射免疫球蛋白2g/kg和甲基强的松龙2mg/kg/天以及其他支持治疗,他成功地治疗了三天。患者住院20天后出院,健康状况好转。我们的病例报告将加强冠状病毒感染与MIS-C之间的暴露-结果关系,并且我们的病例所采取的策略将是有效管理MIS-C的未来方向。
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