Comparison of the Effects of Midazolam, Propofol, and Dexmede-tomidine on Hemodynamics Variation in Patients Undergoing Cataract Surgery under Local Anesthesia at 5th Azar Hospital in Gorgan in 2021-2022

Abstract

Introduction: Cataract surgery is a common surgery, especially among the elderly, and the choice of anesthesia medications is critical in such patients. In this study, the effects of midazolam, propofol, and dexmedetomidine were investigated for sedation in patients undergoing cataract surgery under local anesthesia. Method: Ninety patients were included in this study and underwent cataract surgery using class II and III anesthesia (according to the ASA criteria). They were also randomly assigned to three groups. The first group received midazolam, the second group received propofol, and the third group received dexmedetomidine. During the surgery and recovery phase, blood pressure, arterial blood oxygen saturation, heart rate, and the occurrence of complications were recorded. Data were analyzed using the SPSS software (version 23) at a significance level of 0.05. Results: Alterations in arterial blood oxygen saturation (SpO2) levels were not significantly different among the three groups (P>0.05); however, there were fewer changes in SpO2 levels at recovery in the propofol group (P<0.05). Moreover, alterations in blood pressure did not differ significantly across the three groups during the surgery (P>0.05), whereas during the recovery, they were lower in the group receiving dexmedetomidine (P>0.05). Finally, Heart rates were not significantly different among the three groups during surgery and recovery (P>0.05). Conclusion: The results demonstrated that in patients with hypertension and tachycardia, dexmedetomidine may be a better choice for sedation.