Cefditoren pivoxil induced toxic epidermal necrolysis: a case report

Amarthya S. Racha, P. Ashwani, Polevoina Swarnalatha
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Abstract

Cutaneous adverse drug reactions vary in severity, from mild erythematous skin lesions to life-threatening toxic epidermal necrolysis. Antiepileptics, antipsychotics, antimicrobials, and diuretics are associated with these adverse reactions. We report a case of cefditoren pivoxil-induced toxic epidermal necrolysis in a 46-year-old Indian woman who presented initially with a maculopapular rash that eventually progressed to steroid-refractory toxic epidermal necrolysis. The patient succumbed to her illness on day 33 of the index rash following septic shock.
头孢地托林酯致中毒性表皮坏死松解1例
皮肤药物不良反应的严重程度各不相同,从轻度红斑性皮肤病变到危及生命的毒性表皮坏死松解。抗癫痫药、抗精神病药、抗菌剂和利尿剂与这些不良反应有关。我们报告一例头孢地酚酯诱导的中毒性表皮坏死松解症,患者为一名46岁的印度妇女,最初表现为斑疹疹,最终发展为类固醇难治性中毒性表皮坏死松解症。患者在感染性休克后出现皮疹的第33天死亡。
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