Bimodal surface modification strategies towards improving the antibacterial activity of graphene oxide

IF 0.7 4区材料科学 Q4 METALLURGY & METALLURGICAL ENGINEERING

International Journal of Materials Research Pub Date : 2023-08-29 DOI:10.1557/s43578-023-01138-y

Finaz Khan, S. Prusty, Pritha Saha, D. Bera, B. Datta, R. S. Saraffin, Arijit Kapuria, K. Dutta, Susmita Das

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引用次数: 0

Abstract

Herein, we have demonstrated and compared bimodal strategies towards augmenting the antimicrobial activity of graphene oxide (GO). Among the two modifications viz. through alteration of GO surface functionalities and secondly through surface modification of GO with an ampicillin-based antibacterial ionic liquid (IL), the IL modification was most effective in enhancing the bactericidal effect. pH and the zeta potential values of the nanodispersions support the alteration of surface functionalities of GO by variation in reaction conditions and SEM, XRD, Raman spectra establish the resulting sheet thickness, morphology, stacking and planarity. The surface modification of GO with trihexyltetradecyl phosphonium ampicillin ([TTP][Amp]) IL as indicated by FTIR, SEM, pH and zeta potential measurements imply in nearly five times lower MBC value compared to average MBC value of the four GO variants. Hence, judicious IL modification can be an effective approach towards augmenting antibacterial property of GO for enduring antifouling coatings and membranes.

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提高氧化石墨烯抗菌活性的双峰表面修饰策略

在此，我们展示并比较了增强氧化石墨烯(GO)抗菌活性的双峰策略。在改变氧化石墨烯表面官能团的改性和用氨苄青霉素类抗菌离子液体(IL)对氧化石墨烯进行表面改性的两种改性方式中，IL改性对氧化石墨烯的杀菌效果最有效。纳米分散体的pH和zeta电位值通过反应条件的变化支持氧化石墨烯表面官能团的变化，SEM、XRD、Raman光谱确定了生成的薄片厚度、形貌、堆叠和平面度。FTIR、SEM、pH和zeta电位测量表明，三己基十四烷基氨苄西林磷([TTP][Amp]) IL对氧化石墨烯进行表面改性后，其MBC值比四种氧化石墨烯变体的平均MBC值低近五倍。因此，明智的IL改性可以有效地提高氧化石墨烯的抗菌性能，用于持久的防污涂层和膜。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Materials Research 工程技术-冶金工程

CiteScore

1.30

自引率

12.50%

发文量

119

审稿时长

6.4 months

期刊介绍： The International Journal of Materials Research (IJMR) publishes original high quality experimental and theoretical papers and reviews on basic and applied research in the field of materials science and engineering, with focus on synthesis, processing, constitution, and properties of all classes of materials. Particular emphasis is placed on microstructural design, phase relations, computational thermodynamics, and kinetics at the nano to macro scale. Contributions may also focus on progress in advanced characterization techniques. All articles are subject to thorough, independent peer review.