Reflections about the Detection of Flower Cells in B-Cells Lymphomas

Abstract

Flower or floral cells are multilobulated/petal-like nuclei, medium to large size cells usually present in cases of adult T-cell leukemia (ATL). However, since 2008, four cases of these cells, previously "restricted" to adult T leukemia, have been reported in B-cells lymphomas, many of them highly aggressive. Thus, this brief article aims to show how should be the assessment of these atypical cells in B lineage lymphomas and instigate more robust studies on the subject.