Spectroscopic Analysis and ADME Studies of Phytochemicals in Methanolic Leaves Extract of Sonneratia apetala Buch.-Ham

Nishant Nandkhile, Sachin Vanpure, Prathmesh Khetmalis, R. Bhondwe
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引用次数: 3

Abstract

The plants are enormous source of medicinally important ingredients. The separation of active plants compounds leads to discovery of many drugs derived directly from plants. In the current study, The HPLC analysis is carried for the methanolic extracts of gives different peaks at 254 nm, it may be alcoholic compound. The FTIR spectrum confirmed the presence of alcohol, alkanes, carboxylic acid, aromatics, esters and ethers in methanolic extract of Sonneratia apetala. UV-Visible profile showed different peaks ranging from 200-800 nm with different absorption respectively. In silico study, especially physicochemical properties, lipophilicity, water solubility, pharmacokinetics, drug likeness and medicinal chemistry performed by using the Swiss ADME online tool.
无瓣海桑甲醇叶提取物中植物化学物质的光谱分析及ADME研究
这些植物是重要药用成分的巨大来源。活性植物化合物的分离导致许多直接从植物中提取的药物的发现。本研究对其甲醇提取物进行了高效液相色谱分析,在254 nm处出现不同的峰,可能为醇性化合物。红外光谱分析证实无花瓣海桑甲醇提取物中存在醇类、烷烃类、羧酸类、芳烃类、酯类和醚类化合物。紫外-可见光谱在200 ~ 800 nm范围内呈现不同的吸收峰。通过使用瑞士ADME在线工具进行硅片研究,特别是物理化学性质,亲脂性,水溶性,药代动力学,药物相似性和药物化学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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