Probing Subsistence of Host Guest Inclusion Complexes of Oligosaccharides with Allopurinol for Regulatory Release with the Manifestation of Solvation Consequences
J. Mondal, Ashutosh Dutta, K. Das, D. Das, P. Karmakar, S. Sengupta, A. Bhattacharya, R. Das, M. Roy
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引用次数: 0
Abstract
Article history: Received 09 February 2019 Accepted 01 March 2019 Available online 05 May 2019 The inspection of molecular interaction widespread in allopurinol and in aqueous solutions of α-, and HP-β-cyclodextrin have been probed by thermophysical properties. The established complexes obtained with 1:1 stoichiometry. Role of solvent (aqueous solution of α-CD, -CD, HP-β-CD) and contribution of solute–solute and solute–solvent interactions to solution complexes, have also been analyzed via stability constant-NMR, UV, steady state fluorescence, FTIR, HRMS, SEM, PXRD, cytotoxicity, hydrophobic effect, hydrogen-bonding, structural effects in creation of inclusion complexes.
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