Neonatal Near Miss among Newborns of Women with Type 1 Diabetes Mellitus

IF 1.6 Q3 OBSTETRICS & GYNECOLOGY

Obstetrics and Gynecology International Pub Date : 2019-07-31 DOI:10.1155/2019/8594158

L. R. Morais, Beatriz Patz, F. F. Campanharo, P. Dualib, S. Sun, R. Mattar

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引用次数: 9

Abstract

Objective To investigate the frequency of neonatal near miss (NNM) and associate it with maternal morbidity in newborns of women with type 1 diabetes mellitus (T1DM). Methods This was a cross-sectional retrospective study from a secondary analysis of data retrieved from medical records of pregnant women with T1DM cared at a Brazilian university hospital between 2005 and 2015. Maternal near miss (MNM) and potentially life-threatening conditions (PTLC) were classified according to the World Health Organization criteria. NNM was classified according to the Pan American Health Organization Neonatal Near Miss Working Group criteria. Association of maternal morbidity with NNM was assessed using chi-square test. Results There were 122 newborns (NB) among 137 T1DM pregnancies. Thirty-seven NB presented NNM—incidence of 303 NNM per 1000 live births (37/122). NNM was associated with MNM (P < 0.001, OR (95% CI): 17.15 (1.85–159.12)). PLTC did not increase the odds of NNM (P=0.07; OR (95% CI): 2.1281 (0.92–4.91)). Seven newborns died, six of them from pregnancies without severe maternal morbidity. 71% of the neonatal death (5/7) occurred in malformed neonates. Conclusion MNM was associated with NNM among women with T1DM, and PLTC, paradoxically, did not increase NNM.

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1型糖尿病女性新生儿近Miss发生率

目的探讨1型糖尿病(T1DM)新生儿近漏产(NNM)发生率及其与孕产妇发病率的关系。方法:本研究是一项横断面回顾性研究，对2005年至2015年在巴西某大学医院就诊的T1DM孕妇的医疗记录进行了二次分析。根据世界卫生组织的标准，对产妇险些脱险(MNM)和可能危及生命的情况(PTLC)进行分类。根据泛美卫生组织新生儿近Miss工作组的标准对NNM进行分类。采用卡方检验评估产妇发病率与NNM的关系。结果137例T1DM妊娠共122例新生儿(NB)。37个新生儿的NNM发病率为每1000例活产303例NNM(37/122)。NNM与MNM相关(P < 0.001, OR (95% CI): 17.15(1.85-159.12))。PLTC未增加NNM的发生率(P=0.07;Or (95% ci): 2.1281(0.92-4.91))。7名新生儿死亡，其中6名死于妊娠，但没有严重的产妇疾病。71%的新生儿死亡(5/7)发生在畸形新生儿中。结论T1DM患者的MNM与NNM相关，而PLTC并没有增加NNM。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetrics and Gynecology International OBSTETRICS & GYNECOLOGY-

CiteScore

3.60

自引率

0.00%

发文量

审稿时长

19 weeks

期刊介绍： Obstetrics and Gynecology International is a peer-reviewed, Open Access journal that aims to provide a forum for scientists and clinical professionals working in obstetrics and gynecology. The journal publishes original research articles, review articles, and clinical studies related to obstetrics, maternal-fetal medicine, general gynecology, gynecologic oncology, uro-gynecology, reproductive medicine and infertility, reproductive endocrinology, and sexual medicine.