Application of Electrosprayed Nanoparticles as Targeted Drug Delivery Systems: A Mini Review

Sanaz Khademolqorani, S. Banitaba
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引用次数: 4

Abstract

Nanoparticles (NPs) are referred to as tiny materials in size ranging from 1 to 100 nm. Unique characteristics of the NPs, including small sizes and high surface area, appropriate reactivity, proper stability, great strength, and many more, have resulted in their wide use in numerous fields. Among different techniques reported for synthesizing the nanoparticles, electro-hydrodynamic atomization or electrospray has been identified as a well-practiced and high efficient technique for the formation of fine and homogenous NPs from a liquid under the influence of electrical forces. This process allows feasible encapsulation of different drugs, vitamins, and proteins applicable in the targeted drug delivery systems. Since the release rate of the loaded pharmaceutical materials could be easily tuned via varying the properties of core and shell components. Herein, we summarized the importance of the electrospray technique for the production of drug-loaded nanoparticles applicable in controlled drug delivery systems.
电喷涂纳米粒子作为靶向给药系统的应用综述
纳米粒子(NPs)是指尺寸在1到100纳米之间的微小材料。NPs的独特特性,包括小尺寸和高表面积,适当的反应性,适当的稳定性,高强度等,使其在许多领域得到广泛应用。在合成纳米颗粒的不同技术中,电流体动力雾化或电喷雾已被确定为一种实践良好且高效的技术,可以在电作用力的影响下从液体中形成精细且均匀的纳米颗粒。该工艺允许在靶向药物输送系统中适用的不同药物、维生素和蛋白质的可行封装。由于负载药物的释放速率可以通过改变核和壳组分的性质来容易地调节。在此,我们总结了电喷雾技术在生产可用于受控药物输送系统的载药纳米颗粒中的重要性。
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