Jan Hrudka, Alžběta Bezvodová, Monika Arenbergerová, Eva Sticová, Dave Bandke
{"title":"[Sebaceous carcinoma in situ in extraocular skin : Case report and discussion of the new entity].","authors":"Jan Hrudka, Alžběta Bezvodová, Monika Arenbergerová, Eva Sticová, Dave Bandke","doi":"10.1007/s00105-019-4464-y","DOIUrl":null,"url":null,"abstract":"<p><p>Sebaceous carcinoma in situ (SCIS) is a rare intraepidermal neoplasia, mostly occurring on the eyelid and the face. Despite abundant literature on invasive sebaceous carcinoma, there are relatively few articles about SCIS. We report the case of 78-year-old woman suffering from SCIS of the left cheek, presenting as an erythematous skin lesion. The histological examination revealed intraepidermal and intraadnexal population of atypical cells with foamy cytoplasm and with immunohistochemical adipophilin-, cytokeratin-7- and EMA-positivity in the tumor cells.</p>","PeriodicalId":11114,"journal":{"name":"Der Hautarzt","volume":"25 1","pages":"57-62"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Der Hautarzt","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00105-019-4464-y","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Sebaceous carcinoma in situ (SCIS) is a rare intraepidermal neoplasia, mostly occurring on the eyelid and the face. Despite abundant literature on invasive sebaceous carcinoma, there are relatively few articles about SCIS. We report the case of 78-year-old woman suffering from SCIS of the left cheek, presenting as an erythematous skin lesion. The histological examination revealed intraepidermal and intraadnexal population of atypical cells with foamy cytoplasm and with immunohistochemical adipophilin-, cytokeratin-7- and EMA-positivity in the tumor cells.
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